How somatic cortical maps differ in autistic and typical brains

Mehmet Akif Coskun, Larry Varghese, Stacy Reddoch, Eduardo M. Castillo, Deborah A. Pearson, Katherine A. Loveland, Andrew C. Papanicolaou, Bhavin R. Sheth

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The comorbidity of 'core characteristics' and sensorimotor abnormalities in autism implies abnormalities in brain development of a general and pervasive nature and atypical organization of sensory cortex. By using magnetoencephalography, we examined the cortical response to passive tactile stimulation of the thumb and index finger of the dominant hand and lip of the individuals with autism spectrum disorder and typically developing persons. The distance between the cortical representations of thumb and the lip was significantly larger in the autism group than in typicals. Moreover, in cortex, the thumb is typically closer to the lip than the index finger. This was not observed in persons with autism. Our findings are arguably the first demonstration of abnormality in sensory organization in the brains of persons with autism.

Original languageEnglish (US)
Pages (from-to)175-179
Number of pages5
JournalNeuroReport
Volume20
Issue number2
DOIs
StatePublished - Jan 28 2009
Externally publishedYes

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Autistic Disorder
Thumb
Lip
Brain
Fingers
Magnetoencephalography
Touch
Comorbidity
Hand

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Coskun, M. A., Varghese, L., Reddoch, S., Castillo, E. M., Pearson, D. A., Loveland, K. A., ... Sheth, B. R. (2009). How somatic cortical maps differ in autistic and typical brains. NeuroReport, 20(2), 175-179. https://doi.org/10.1097/WNR.0b013e32831f47d1

How somatic cortical maps differ in autistic and typical brains. / Coskun, Mehmet Akif; Varghese, Larry; Reddoch, Stacy; Castillo, Eduardo M.; Pearson, Deborah A.; Loveland, Katherine A.; Papanicolaou, Andrew C.; Sheth, Bhavin R.

In: NeuroReport, Vol. 20, No. 2, 28.01.2009, p. 175-179.

Research output: Contribution to journalArticle

Coskun, MA, Varghese, L, Reddoch, S, Castillo, EM, Pearson, DA, Loveland, KA, Papanicolaou, AC & Sheth, BR 2009, 'How somatic cortical maps differ in autistic and typical brains', NeuroReport, vol. 20, no. 2, pp. 175-179. https://doi.org/10.1097/WNR.0b013e32831f47d1
Coskun MA, Varghese L, Reddoch S, Castillo EM, Pearson DA, Loveland KA et al. How somatic cortical maps differ in autistic and typical brains. NeuroReport. 2009 Jan 28;20(2):175-179. https://doi.org/10.1097/WNR.0b013e32831f47d1
Coskun, Mehmet Akif ; Varghese, Larry ; Reddoch, Stacy ; Castillo, Eduardo M. ; Pearson, Deborah A. ; Loveland, Katherine A. ; Papanicolaou, Andrew C. ; Sheth, Bhavin R. / How somatic cortical maps differ in autistic and typical brains. In: NeuroReport. 2009 ; Vol. 20, No. 2. pp. 175-179.
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