Hypermagnesemia and hypocalcemia as predictors of high mortality in critically ill pediatric patients

C. W. Broner, G. L. Stidham, D. F. Westenkirchner, Elizabeth Tolley

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Ca and Mg are biologically important minerals that are involved in maintaining the stability of membranes, muscle contractions, and enzyme activity in nearly all cells. Derangements of Ca and Mg homeostasis can precipitate serious and life-threatening problems in the critically ill patients. We examined serum ionized Ca and Mg levels in pediatric patients consecutively admitted to a pediatric ICU. Abnormal Mg and ionized Ca levels on admission were found in 43.3% and 17% of the patients, respectively. Hypocalcemia and hypermagnesemia were both associated with poor outcome as measured by either survival or length of ICU stay. In addition, ionized Ca levels could not be predicted from total Ca measurement either alone or in combination with serum albumin and pH.

Original languageEnglish (US)
Pages (from-to)921-928
Number of pages8
JournalCritical Care Medicine
Volume18
Issue number9
DOIs
StatePublished - Jan 1 1990
Externally publishedYes

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Hypocalcemia
Critical Illness
Pediatrics
Mortality
Muscle Contraction
Serum Albumin
Minerals
Length of Stay
Homeostasis
Membranes
Survival
Enzymes
Serum

All Science Journal Classification (ASJC) codes

  • Critical Care and Intensive Care Medicine

Cite this

Hypermagnesemia and hypocalcemia as predictors of high mortality in critically ill pediatric patients. / Broner, C. W.; Stidham, G. L.; Westenkirchner, D. F.; Tolley, Elizabeth.

In: Critical Care Medicine, Vol. 18, No. 9, 01.01.1990, p. 921-928.

Research output: Contribution to journalArticle

Broner, C. W. ; Stidham, G. L. ; Westenkirchner, D. F. ; Tolley, Elizabeth. / Hypermagnesemia and hypocalcemia as predictors of high mortality in critically ill pediatric patients. In: Critical Care Medicine. 1990 ; Vol. 18, No. 9. pp. 921-928.
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