Identification of Risk Factors for Extrapulmonary Tuberculosis

Zhenhua Yang, Ying Kong, Frank Wilson, Betsy Foxman, Annadell H. Fowler, Carl F. Marrs, M. Donald Cave, Joseph H. Bates

Research output: Contribution to journalArticle

204 Citations (Scopus)

Abstract

The proportion of extrapulmonary tuberculosis cases in the United States has increased from 16% of tuberculosis cases, in 1991, to 20%, in 2001. To determine associations between the demographic, clinical, and life style characteristics of patients with tuberculosis and the occurrence of extrapulmonary tuberculosis, a retrospective case-control study was conducted. This study included 705 patients with tuberculosis, representing 98% of the culture-proven cases of tuberculosis in Arkansas from 1 January 1996 through 31 December 2000. A comparison between 85 patients with extrapulmonary tuberculosis (case patients) and 620 patients with pulmonary tuberculosis (control patients) showed women (OR, 1.98; 95% CI, 1.25-3.13), non-Hispanic blacks (OR, 2.38; 95% CI, 1.42-3.97), and HIV-positive persons (OR, 4.93; 95% CI, 1.95-12.46) to have a significantly higher risk for extrapulmonary tuberculosis than men, non-Hispanic whites, and HIV-negative persons. This study expands the knowledge base regarding the epidemiology of extrapulmonary tuberculosis and enhances our understanding of the relative contribution of host-related factors to the pathogenesis of tuberculosis.

Original languageEnglish (US)
Pages (from-to)199-205
Number of pages7
JournalClinical Infectious Diseases
Volume38
Issue number2
DOIs
StatePublished - Jan 15 2004

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Tuberculosis
HIV
Knowledge Bases
Pulmonary Tuberculosis
Case-Control Studies
Life Style
Epidemiology
Demography

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Yang, Z., Kong, Y., Wilson, F., Foxman, B., Fowler, A. H., Marrs, C. F., ... Bates, J. H. (2004). Identification of Risk Factors for Extrapulmonary Tuberculosis. Clinical Infectious Diseases, 38(2), 199-205. https://doi.org/10.1086/380644

Identification of Risk Factors for Extrapulmonary Tuberculosis. / Yang, Zhenhua; Kong, Ying; Wilson, Frank; Foxman, Betsy; Fowler, Annadell H.; Marrs, Carl F.; Cave, M. Donald; Bates, Joseph H.

In: Clinical Infectious Diseases, Vol. 38, No. 2, 15.01.2004, p. 199-205.

Research output: Contribution to journalArticle

Yang, Z, Kong, Y, Wilson, F, Foxman, B, Fowler, AH, Marrs, CF, Cave, MD & Bates, JH 2004, 'Identification of Risk Factors for Extrapulmonary Tuberculosis', Clinical Infectious Diseases, vol. 38, no. 2, pp. 199-205. https://doi.org/10.1086/380644
Yang Z, Kong Y, Wilson F, Foxman B, Fowler AH, Marrs CF et al. Identification of Risk Factors for Extrapulmonary Tuberculosis. Clinical Infectious Diseases. 2004 Jan 15;38(2):199-205. https://doi.org/10.1086/380644
Yang, Zhenhua ; Kong, Ying ; Wilson, Frank ; Foxman, Betsy ; Fowler, Annadell H. ; Marrs, Carl F. ; Cave, M. Donald ; Bates, Joseph H. / Identification of Risk Factors for Extrapulmonary Tuberculosis. In: Clinical Infectious Diseases. 2004 ; Vol. 38, No. 2. pp. 199-205.
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