Identifying biomarkers as diagnostic tools in kidney transplantation

Valeria Mas, Thomas F. Mueller, Kellie J. Archer, Daniel Maluf

Research output: Contribution to journalReview article

21 Citations (Scopus)

Abstract

There is a critical need for biomarkers for early diagnosis, treatment response, and surrogate end point and outcome prediction in organ transplantation, leading to a tailored and individualized treatment. Genomic and proteomic platforms have provided multiple promising new biomarkers during the last few years. However, there is still no routine application of any of these markers in clinical transplantation. This article will discuss the existing gap between biomarker discovery and clinical application in the kidney transplant setting. Approaches to implementing biomarker monitoring into clinical practice will also be discussed.

Original languageEnglish (US)
Pages (from-to)183-196
Number of pages14
JournalExpert Review of Molecular Diagnostics
Volume11
Issue number2
DOIs
StatePublished - Mar 1 2011

Fingerprint

Kidney Transplantation
Biomarkers
Organ Transplantation
Proteomics
Early Diagnosis
Transplantation
Transplants
Kidney
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Molecular Medicine
  • Molecular Biology
  • Genetics

Cite this

Identifying biomarkers as diagnostic tools in kidney transplantation. / Mas, Valeria; Mueller, Thomas F.; Archer, Kellie J.; Maluf, Daniel.

In: Expert Review of Molecular Diagnostics, Vol. 11, No. 2, 01.03.2011, p. 183-196.

Research output: Contribution to journalReview article

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