Idiopathic intracranial hypertension with primary aldosteronism

Report of 2 cases

Karl Weber, Karan D. Singh, J. Christopher Hey

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Although unconfirmed, the syndrome idiopathic intracranial hypertension (IIH), commonly seen in overweight 20- to 50-year-old women, has been proposed to have its origins in an endocrine-based disturbance of electrolytes. Herein we report on 2 women with IIH and primary aldosteronism (PAL). Aged 57 and 55 (patients 1 and 2), each had a longstanding history of mild-to-moderate arterial hypertension, recurrent hypokalemia, and headaches. They were found to have IIH at ages 51 and 45. PAL was diagnosed at ages 57 and 35, respectively, due to proven left adrenal adenoma in patient 1; and presumptive adrenal nodular hyperplasia in patient 2. This is the first report to appear in the English medical literature that describes an association between IIH and PAL. It raises the prospect that in some cases of IIH associated with arterial hypertension, an autonomous production of aldosterone should be considered.

Original languageEnglish (US)
Pages (from-to)45-50
Number of pages6
JournalAmerican Journal of the Medical Sciences
Volume324
Issue number1
DOIs
StatePublished - Jan 1 2002

Fingerprint

Pseudotumor Cerebri
Hyperaldosteronism
Hypertension
Hypokalemia
Aldosterone
Adenoma
Electrolytes
Hyperplasia
Headache

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Idiopathic intracranial hypertension with primary aldosteronism : Report of 2 cases. / Weber, Karl; Singh, Karan D.; Hey, J. Christopher.

In: American Journal of the Medical Sciences, Vol. 324, No. 1, 01.01.2002, p. 45-50.

Research output: Contribution to journalArticle

@article{77b4294946594c6aa928da29cb67679f,
title = "Idiopathic intracranial hypertension with primary aldosteronism: Report of 2 cases",
abstract = "Although unconfirmed, the syndrome idiopathic intracranial hypertension (IIH), commonly seen in overweight 20- to 50-year-old women, has been proposed to have its origins in an endocrine-based disturbance of electrolytes. Herein we report on 2 women with IIH and primary aldosteronism (PAL). Aged 57 and 55 (patients 1 and 2), each had a longstanding history of mild-to-moderate arterial hypertension, recurrent hypokalemia, and headaches. They were found to have IIH at ages 51 and 45. PAL was diagnosed at ages 57 and 35, respectively, due to proven left adrenal adenoma in patient 1; and presumptive adrenal nodular hyperplasia in patient 2. This is the first report to appear in the English medical literature that describes an association between IIH and PAL. It raises the prospect that in some cases of IIH associated with arterial hypertension, an autonomous production of aldosterone should be considered.",
author = "Karl Weber and Singh, {Karan D.} and Hey, {J. Christopher}",
year = "2002",
month = "1",
day = "1",
doi = "10.1097/00000441-200207000-00007",
language = "English (US)",
volume = "324",
pages = "45--50",
journal = "American Journal of the Medical Sciences",
issn = "0002-9629",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Idiopathic intracranial hypertension with primary aldosteronism

T2 - Report of 2 cases

AU - Weber, Karl

AU - Singh, Karan D.

AU - Hey, J. Christopher

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Although unconfirmed, the syndrome idiopathic intracranial hypertension (IIH), commonly seen in overweight 20- to 50-year-old women, has been proposed to have its origins in an endocrine-based disturbance of electrolytes. Herein we report on 2 women with IIH and primary aldosteronism (PAL). Aged 57 and 55 (patients 1 and 2), each had a longstanding history of mild-to-moderate arterial hypertension, recurrent hypokalemia, and headaches. They were found to have IIH at ages 51 and 45. PAL was diagnosed at ages 57 and 35, respectively, due to proven left adrenal adenoma in patient 1; and presumptive adrenal nodular hyperplasia in patient 2. This is the first report to appear in the English medical literature that describes an association between IIH and PAL. It raises the prospect that in some cases of IIH associated with arterial hypertension, an autonomous production of aldosterone should be considered.

AB - Although unconfirmed, the syndrome idiopathic intracranial hypertension (IIH), commonly seen in overweight 20- to 50-year-old women, has been proposed to have its origins in an endocrine-based disturbance of electrolytes. Herein we report on 2 women with IIH and primary aldosteronism (PAL). Aged 57 and 55 (patients 1 and 2), each had a longstanding history of mild-to-moderate arterial hypertension, recurrent hypokalemia, and headaches. They were found to have IIH at ages 51 and 45. PAL was diagnosed at ages 57 and 35, respectively, due to proven left adrenal adenoma in patient 1; and presumptive adrenal nodular hyperplasia in patient 2. This is the first report to appear in the English medical literature that describes an association between IIH and PAL. It raises the prospect that in some cases of IIH associated with arterial hypertension, an autonomous production of aldosterone should be considered.

UR - http://www.scopus.com/inward/record.url?scp=0036311120&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036311120&partnerID=8YFLogxK

U2 - 10.1097/00000441-200207000-00007

DO - 10.1097/00000441-200207000-00007

M3 - Article

VL - 324

SP - 45

EP - 50

JO - American Journal of the Medical Sciences

JF - American Journal of the Medical Sciences

SN - 0002-9629

IS - 1

ER -