Imaging of ambiguous genitalia

Classification and diagnostic approach

Govind B. Chavhan, Dimitri A. Parra, Kamaldine Oudjhane, Stephen Miller, Paul S. Babyn, Joao L.Pippi Salle

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Disorders of sex development (DSDs) are congenital conditions in which the development of chromosomal, gonadal, or anatomic sex is atypical. DSDs can be classified broadly into four categories on the basis of gonadal histologic features: female pseudohermaphroditism (46,XX with two ovaries); male pseudohermaphroditism (46,XY with two testes); true hermaphroditism (ovotesticular DSD) (both ovarian and testicular tissues); and gonadal dysgenesis, either mixed (a testis and a streak gonad) or pure (bilateral streak gonads). Imaging plays an important role in demonstrating the anatomy and associated anoma-lies. Ultrasonography is the primary modality for demonstrating inter-nal organs; genitography is used to assess the urethra, vagina, and any fistulas or complex tracts; and magnetic resonance imaging is used as an adjunct modality to assess for internal gonads and genitalia. Early and appropriate gender assignment is necessary for healthy physical and psychologic development of children with ambiguous genitalia. Gender assignment can be facilitated with a team approach that in-volves a pediatric endocrinologist, geneticist, urologist, psychiatrist, social worker, neonatologist, nurse, and radiologist, allowing timely diagnosis and proper management.

Original languageEnglish (US)
Pages (from-to)1891-1904
Number of pages14
JournalRadiographics
Volume28
Issue number7
DOIs
StatePublished - Nov 1 2008

Fingerprint

Disorders of Sex Development
Gonads
Ovotesticular Disorders of Sex Development
Testis
Mixed Gonadal Dysgenesis
XX Disorders of Sex Development 46
XY Disorders of Sex Development 46
Genitalia
Vagina
Urethra
Child Development
Fistula
Psychiatry
Ovary
Ultrasonography
Anatomy
Nurses
Magnetic Resonance Imaging
Pediatrics

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Chavhan, G. B., Parra, D. A., Oudjhane, K., Miller, S., Babyn, P. S., & Salle, J. L. P. (2008). Imaging of ambiguous genitalia: Classification and diagnostic approach. Radiographics, 28(7), 1891-1904. https://doi.org/10.1148/rg.287085034

Imaging of ambiguous genitalia : Classification and diagnostic approach. / Chavhan, Govind B.; Parra, Dimitri A.; Oudjhane, Kamaldine; Miller, Stephen; Babyn, Paul S.; Salle, Joao L.Pippi.

In: Radiographics, Vol. 28, No. 7, 01.11.2008, p. 1891-1904.

Research output: Contribution to journalArticle

Chavhan, GB, Parra, DA, Oudjhane, K, Miller, S, Babyn, PS & Salle, JLP 2008, 'Imaging of ambiguous genitalia: Classification and diagnostic approach', Radiographics, vol. 28, no. 7, pp. 1891-1904. https://doi.org/10.1148/rg.287085034
Chavhan GB, Parra DA, Oudjhane K, Miller S, Babyn PS, Salle JLP. Imaging of ambiguous genitalia: Classification and diagnostic approach. Radiographics. 2008 Nov 1;28(7):1891-1904. https://doi.org/10.1148/rg.287085034
Chavhan, Govind B. ; Parra, Dimitri A. ; Oudjhane, Kamaldine ; Miller, Stephen ; Babyn, Paul S. ; Salle, Joao L.Pippi. / Imaging of ambiguous genitalia : Classification and diagnostic approach. In: Radiographics. 2008 ; Vol. 28, No. 7. pp. 1891-1904.
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