Immunoglobulin A nephropathy in a renal allograft of a black transplant recipient

Susan Francisco, Barry Wall, C. Robert Cooke

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Although IgA nephropathy (IgA N) is reportedly the most common form of primary glomerulonephritis worldwide, there is a very low incidence oflgA N in Black Americans, and IgA N in Black patients with renal allografts has not been reported. In this report, we present the case of a Black patient with end-stage renal disease presumed secondary to hypertensive nephrosclerosis who developed nephrotic range proteinuria due to IgA N in a cadaveric renal allograft 2 years following transplantation. Biopsy of the allograft in the immediate post-transplantation period had revealed no evidence of IgA N. Chronic active hepatitis related to hepatitis C preceded the development of proteinuria by approximately 1 year, raising the possibility that IgA N in the renal allograft was secondary to the liver disease. The clinical and histological features of primary IgA N and IgA N secondary to liver diseases are discussed.

Original languageEnglish (US)
Pages (from-to)121-125
Number of pages5
JournalAmerican Journal of Nephrology
Volume12
Issue number1-2
DOIs
StatePublished - Jan 1 1992

Fingerprint

IGA Glomerulonephritis
Immunoglobulin A
Allografts
Kidney
Proteinuria
Liver Diseases
Transplantation
Nephrosclerosis
Chronic Hepatitis
Hepatitis C
Glomerulonephritis
Transplant Recipients
Chronic Kidney Failure
Biopsy
Incidence

All Science Journal Classification (ASJC) codes

  • Nephrology

Cite this

Immunoglobulin A nephropathy in a renal allograft of a black transplant recipient. / Francisco, Susan; Wall, Barry; Cooke, C. Robert.

In: American Journal of Nephrology, Vol. 12, No. 1-2, 01.01.1992, p. 121-125.

Research output: Contribution to journalArticle

Francisco, Susan ; Wall, Barry ; Cooke, C. Robert. / Immunoglobulin A nephropathy in a renal allograft of a black transplant recipient. In: American Journal of Nephrology. 1992 ; Vol. 12, No. 1-2. pp. 121-125.
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