A Hodgkin-kór immunohisztológiája. Monoclonális antitestek alkalmazása a Hodgkin-kór patomorfológiai elemzésében.

Translated title of the contribution: Immunohistology of Hodgkin's disease. Use of monoclonal antibodies in the analysis of the pathomorphology of Hodgkin's disease

Research output: Contribution to journalReview article

Abstract

Author studied cryostatic sections of lymph node biopsy of 45 untreated patients suffering in lymphogranulomatosis by known T and B lymphocyte, macrophage-histiocyte, Ia and HLA-DR and transferrine receptor specific monoclonal antibodies (moats). In HK-LP, HK-NS, HK-MC and HK-LD the infiltrations were formed by phenotyped lymphocytes contrary to HK-NP, where HK nodules were composed of B-cells. In HK-LPs T lymphocytes were of T-helper phenotypes, and these T-cells were observed in cases of HH-NS and HK-MC, abounding in lymphocytes, besides a few T-suppressor cells. The number of lymphocyte of latter type increased in HK-NS and and HK-MC, poor in lymphocytes and in HK-LD. The giant cells had positive reaction with Leu3a, Leu5, OKIa, HLA-DR and transferrine receptor specific moats. SR cells are such anaplasic cells or probably tumorous cells developed by cell hybridization, which are able to antigen expression characteristic of various hemopoietic cell line and of activated cells, respectively.

Original languageHungarian
Pages (from-to)182-190
Number of pages9
JournalMorphologiai es Igazsagugyi Orvosi Szemle
Volume30
Issue number3
StatePublished - Jul 1 1990

Fingerprint

Hodgkin Disease
Monoclonal Antibodies
HLA-DR Antigens
Lymphocytes
B-Lymphocytes
T-Lymphocytes
Histiocytes
Lymphocyte Count
Giant Cells
Helper-Inducer T-Lymphocytes
Lymph Nodes
Macrophages
Phenotype
Biopsy
Antigens
Cell Line

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{bc45c91174334965a1d42170da6dc10d,
title = "A Hodgkin-k{\'o}r immunohisztol{\'o}gi{\'a}ja. Monoclon{\'a}lis antitestek alkalmaz{\'a}sa a Hodgkin-k{\'o}r patomorfol{\'o}giai elemz{\'e}s{\'e}ben.",
abstract = "Author studied cryostatic sections of lymph node biopsy of 45 untreated patients suffering in lymphogranulomatosis by known T and B lymphocyte, macrophage-histiocyte, Ia and HLA-DR and transferrine receptor specific monoclonal antibodies (moats). In HK-LP, HK-NS, HK-MC and HK-LD the infiltrations were formed by phenotyped lymphocytes contrary to HK-NP, where HK nodules were composed of B-cells. In HK-LPs T lymphocytes were of T-helper phenotypes, and these T-cells were observed in cases of HH-NS and HK-MC, abounding in lymphocytes, besides a few T-suppressor cells. The number of lymphocyte of latter type increased in HK-NS and and HK-MC, poor in lymphocytes and in HK-LD. The giant cells had positive reaction with Leu3a, Leu5, OKIa, HLA-DR and transferrine receptor specific moats. SR cells are such anaplasic cells or probably tumorous cells developed by cell hybridization, which are able to antigen expression characteristic of various hemopoietic cell line and of activated cells, respectively.",
author = "Louisa Balazs",
year = "1990",
month = "7",
day = "1",
language = "Hungarian",
volume = "30",
pages = "182--190",
journal = "Morphologiai es igazsagugyi orvosi szemle",
issn = "0540-889X",
number = "3",

}

TY - JOUR

T1 - A Hodgkin-kór immunohisztológiája. Monoclonális antitestek alkalmazása a Hodgkin-kór patomorfológiai elemzésében.

AU - Balazs, Louisa

PY - 1990/7/1

Y1 - 1990/7/1

N2 - Author studied cryostatic sections of lymph node biopsy of 45 untreated patients suffering in lymphogranulomatosis by known T and B lymphocyte, macrophage-histiocyte, Ia and HLA-DR and transferrine receptor specific monoclonal antibodies (moats). In HK-LP, HK-NS, HK-MC and HK-LD the infiltrations were formed by phenotyped lymphocytes contrary to HK-NP, where HK nodules were composed of B-cells. In HK-LPs T lymphocytes were of T-helper phenotypes, and these T-cells were observed in cases of HH-NS and HK-MC, abounding in lymphocytes, besides a few T-suppressor cells. The number of lymphocyte of latter type increased in HK-NS and and HK-MC, poor in lymphocytes and in HK-LD. The giant cells had positive reaction with Leu3a, Leu5, OKIa, HLA-DR and transferrine receptor specific moats. SR cells are such anaplasic cells or probably tumorous cells developed by cell hybridization, which are able to antigen expression characteristic of various hemopoietic cell line and of activated cells, respectively.

AB - Author studied cryostatic sections of lymph node biopsy of 45 untreated patients suffering in lymphogranulomatosis by known T and B lymphocyte, macrophage-histiocyte, Ia and HLA-DR and transferrine receptor specific monoclonal antibodies (moats). In HK-LP, HK-NS, HK-MC and HK-LD the infiltrations were formed by phenotyped lymphocytes contrary to HK-NP, where HK nodules were composed of B-cells. In HK-LPs T lymphocytes were of T-helper phenotypes, and these T-cells were observed in cases of HH-NS and HK-MC, abounding in lymphocytes, besides a few T-suppressor cells. The number of lymphocyte of latter type increased in HK-NS and and HK-MC, poor in lymphocytes and in HK-LD. The giant cells had positive reaction with Leu3a, Leu5, OKIa, HLA-DR and transferrine receptor specific moats. SR cells are such anaplasic cells or probably tumorous cells developed by cell hybridization, which are able to antigen expression characteristic of various hemopoietic cell line and of activated cells, respectively.

UR - http://www.scopus.com/inward/record.url?scp=0025456861&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025456861&partnerID=8YFLogxK

M3 - Review article

VL - 30

SP - 182

EP - 190

JO - Morphologiai es igazsagugyi orvosi szemle

JF - Morphologiai es igazsagugyi orvosi szemle

SN - 0540-889X

IS - 3

ER -