In-line X-ray phase-contrast lung imaging in situ with a benchtop system

A. B. Garson, Enrique Izaguirre, S. G. Price, H. Guan, S. K. Vasireddi, M. A. Anastasio

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

X-ray phase-contrast (XPC) imaging methods are well-suited for lung imaging applications due To The weakly absorbing nature of lung Tissue and The strong refractive effects associated with Tissue-Air interfaces. Until recently, XPC lung imaging had only been accomplished at synchrotron facilities. In This work, we investigate The manifestation of speckle in propagation-based XPC images of mouse lungs acquired in situ by use of a benchtop imager. The key contributions of The work are: a) The demonstration That lung speckle can be observed by use of a benchtop XPC imaging system employing a polychromatic Tube-source; and b) a systematic experimental investigation of how The Texture of The speckle pattern depends on The parameters of The imaging system. Our analyses consists of image Texture characterization based on The statistical properties of pixel intensity distributions. Results show how image Texture measures of lung regions are strongly dependent on imaging system parameters associated with XPC sensitivity.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2014
Subtitle of host publicationPhysics of Medical Imaging
PublisherSPIE
Volume9033
ISBN (Print)9780819498267
DOIs
StatePublished - Jan 1 2014
Externally publishedYes
EventMedical Imaging 2014: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 17 2014Feb 20 2014

Other

OtherMedical Imaging 2014: Physics of Medical Imaging
CountryUnited States
CitySan Diego, CA
Period2/17/142/20/14

Fingerprint

phase contrast
lungs
X-Rays
Imaging techniques
X rays
Lung
Speckle
Imaging systems
Image texture
x rays
textures
Tissue
Contrast Sensitivity
Synchrotrons
Image sensors
speckle patterns
Demonstrations
Textures
Pixels
mice

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Garson, A. B., Izaguirre, E., Price, S. G., Guan, H., Vasireddi, S. K., & Anastasio, M. A. (2014). In-line X-ray phase-contrast lung imaging in situ with a benchtop system. In Medical Imaging 2014: Physics of Medical Imaging (Vol. 9033). [90330A] SPIE. https://doi.org/10.1117/12.2043936

In-line X-ray phase-contrast lung imaging in situ with a benchtop system. / Garson, A. B.; Izaguirre, Enrique; Price, S. G.; Guan, H.; Vasireddi, S. K.; Anastasio, M. A.

Medical Imaging 2014: Physics of Medical Imaging. Vol. 9033 SPIE, 2014. 90330A.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Garson, AB, Izaguirre, E, Price, SG, Guan, H, Vasireddi, SK & Anastasio, MA 2014, In-line X-ray phase-contrast lung imaging in situ with a benchtop system. in Medical Imaging 2014: Physics of Medical Imaging. vol. 9033, 90330A, SPIE, Medical Imaging 2014: Physics of Medical Imaging, San Diego, CA, United States, 2/17/14. https://doi.org/10.1117/12.2043936
Garson AB, Izaguirre E, Price SG, Guan H, Vasireddi SK, Anastasio MA. In-line X-ray phase-contrast lung imaging in situ with a benchtop system. In Medical Imaging 2014: Physics of Medical Imaging. Vol. 9033. SPIE. 2014. 90330A https://doi.org/10.1117/12.2043936
Garson, A. B. ; Izaguirre, Enrique ; Price, S. G. ; Guan, H. ; Vasireddi, S. K. ; Anastasio, M. A. / In-line X-ray phase-contrast lung imaging in situ with a benchtop system. Medical Imaging 2014: Physics of Medical Imaging. Vol. 9033 SPIE, 2014.
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