In vitro PAI-1 inhibitory activity of oxalamide derivatives

Mukul R. Jain, Shankar Shetty, Ganes Chakrabarti, Vrajesh Pandya, Ajay Sharma, Bhavesh Parmar, Soma Srivastava, Mehul Raviya, Hiteshkumar Soni, Pankaj R. Patel

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A number of oxalamide derivatives have been synthesized and evaluated for PAI-1 inhibitory activity. In vitro PAI-1 inhibitory activities of oxalamide derivatives are evaluated by chromogenic assay. Few compounds have shown significant PAI-1 inhibitory activity.

Original languageEnglish (US)
Pages (from-to)880-884
Number of pages5
JournalEuropean Journal of Medicinal Chemistry
Volume43
Issue number4
DOIs
StatePublished - Apr 1 2008

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Plasminogen Activator Inhibitor 1
Derivatives
Chromogenics
Assays
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

Cite this

Jain, M. R., Shetty, S., Chakrabarti, G., Pandya, V., Sharma, A., Parmar, B., ... Patel, P. R. (2008). In vitro PAI-1 inhibitory activity of oxalamide derivatives. European Journal of Medicinal Chemistry, 43(4), 880-884. https://doi.org/10.1016/j.ejmech.2007.05.011

In vitro PAI-1 inhibitory activity of oxalamide derivatives. / Jain, Mukul R.; Shetty, Shankar; Chakrabarti, Ganes; Pandya, Vrajesh; Sharma, Ajay; Parmar, Bhavesh; Srivastava, Soma; Raviya, Mehul; Soni, Hiteshkumar; Patel, Pankaj R.

In: European Journal of Medicinal Chemistry, Vol. 43, No. 4, 01.04.2008, p. 880-884.

Research output: Contribution to journalArticle

Jain, MR, Shetty, S, Chakrabarti, G, Pandya, V, Sharma, A, Parmar, B, Srivastava, S, Raviya, M, Soni, H & Patel, PR 2008, 'In vitro PAI-1 inhibitory activity of oxalamide derivatives', European Journal of Medicinal Chemistry, vol. 43, no. 4, pp. 880-884. https://doi.org/10.1016/j.ejmech.2007.05.011
Jain MR, Shetty S, Chakrabarti G, Pandya V, Sharma A, Parmar B et al. In vitro PAI-1 inhibitory activity of oxalamide derivatives. European Journal of Medicinal Chemistry. 2008 Apr 1;43(4):880-884. https://doi.org/10.1016/j.ejmech.2007.05.011
Jain, Mukul R. ; Shetty, Shankar ; Chakrabarti, Ganes ; Pandya, Vrajesh ; Sharma, Ajay ; Parmar, Bhavesh ; Srivastava, Soma ; Raviya, Mehul ; Soni, Hiteshkumar ; Patel, Pankaj R. / In vitro PAI-1 inhibitory activity of oxalamide derivatives. In: European Journal of Medicinal Chemistry. 2008 ; Vol. 43, No. 4. pp. 880-884.
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