Increased intestinal permeability in ankylosing spondylitis - Primary lesion or drug effect?

A. J. Morris, Colin Howden, C. Robertson, A. Duncan, H. Torley, R. D. Sturrock, R. I. Russell

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

We have found increased small intestinal permeability to 51Cr-ethylenediaminetetra acetate in patients with ankylosing spondylitis compared with controls. There is no significant difference between patients with ankylosing spondylitis and patients with rheumatoid arthritis taking non-steroidal anti-inflammatory drugs (NSAID). The increased intestinal permeability in ankylosing spondylitis is independent of disease activity. These findings suggest that the increased permeability is caused by NSAID treatment and is probably not a primary lesion of small bowel mucosa.

Original languageEnglish (US)
Pages (from-to)1470-1472
Number of pages3
JournalGut
Volume32
Issue number12
DOIs
StatePublished - Jan 1 1991

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Ankylosing Spondylitis
Permeability
Anti-Inflammatory Agents
Pharmaceutical Preparations
Rheumatoid Arthritis
Mucous Membrane
Acetates
Therapeutics

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Morris, A. J., Howden, C., Robertson, C., Duncan, A., Torley, H., Sturrock, R. D., & Russell, R. I. (1991). Increased intestinal permeability in ankylosing spondylitis - Primary lesion or drug effect? Gut, 32(12), 1470-1472. https://doi.org/10.1136/gut.32.12.1470

Increased intestinal permeability in ankylosing spondylitis - Primary lesion or drug effect? / Morris, A. J.; Howden, Colin; Robertson, C.; Duncan, A.; Torley, H.; Sturrock, R. D.; Russell, R. I.

In: Gut, Vol. 32, No. 12, 01.01.1991, p. 1470-1472.

Research output: Contribution to journalArticle

Morris, AJ, Howden, C, Robertson, C, Duncan, A, Torley, H, Sturrock, RD & Russell, RI 1991, 'Increased intestinal permeability in ankylosing spondylitis - Primary lesion or drug effect?', Gut, vol. 32, no. 12, pp. 1470-1472. https://doi.org/10.1136/gut.32.12.1470
Morris, A. J. ; Howden, Colin ; Robertson, C. ; Duncan, A. ; Torley, H. ; Sturrock, R. D. ; Russell, R. I. / Increased intestinal permeability in ankylosing spondylitis - Primary lesion or drug effect?. In: Gut. 1991 ; Vol. 32, No. 12. pp. 1470-1472.
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