Indications of spatial relations among structures recognizing amino acids and Na+ at a transport receptor site

E. L. Thomas, H. N. Christensen

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The orientation of the hydroxyl group on carbons 3 or 4 of proline, whether cis or trans, is decisive to the interaction between the amino acid and Na+ for a Na+-linked transport system of the pigeon erythrocyte and the rabbit reticulocyte. Consideration of this response in relation to other strong effects of the position of the hydroxyl group in two transport systems suggests that at the transport receptor site under study, the two substrates bind in juxtaposition, Na+ trans to the carboxyl group of the amino acid.

Original languageEnglish (US)
Pages (from-to)277-283
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume40
Issue number2
DOIs
StatePublished - Jul 27 1970

Fingerprint

Hydroxyl Radical
Amino Acids
Reticulocytes
Columbidae
Proline
Carbon
Erythrocytes
Rabbits
Substrates

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Indications of spatial relations among structures recognizing amino acids and Na+ at a transport receptor site. / Thomas, E. L.; Christensen, H. N.

In: Biochemical and Biophysical Research Communications, Vol. 40, No. 2, 27.07.1970, p. 277-283.

Research output: Contribution to journalArticle

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