Induction therapy for elderly patients with acute myeloid leukemia

Michael Martin, Camille N. Abboud

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Acute myeloid leukemia (AML) is a disease of older adults. Efforts to intensify therapy along traditional avenues have failed to yield improved results. There remains significant clinical equipoise as to how to "induce" patients and whether or not 7 + 3-style regimens improve outcomes over low-dose cytarabine. What is certain is that even in those not receiving active therapy, AML is an exceptionally morbid disease. Diverse interventions are being explored in the management of older patients with AML and the currently available data will be reviewed.

Original languageEnglish (US)
Pages (from-to)311-320
Number of pages10
JournalBlood Reviews
Volume22
Issue number6
DOIs
StatePublished - Nov 1 2008
Externally publishedYes

Fingerprint

Acute Myeloid Leukemia
Cytarabine
Therapeutics

All Science Journal Classification (ASJC) codes

  • Hematology
  • Oncology

Cite this

Induction therapy for elderly patients with acute myeloid leukemia. / Martin, Michael; Abboud, Camille N.

In: Blood Reviews, Vol. 22, No. 6, 01.11.2008, p. 311-320.

Research output: Contribution to journalArticle

Martin, Michael ; Abboud, Camille N. / Induction therapy for elderly patients with acute myeloid leukemia. In: Blood Reviews. 2008 ; Vol. 22, No. 6. pp. 311-320.
@article{507ac4560b424bdcaffb58f577398061,
title = "Induction therapy for elderly patients with acute myeloid leukemia",
abstract = "Acute myeloid leukemia (AML) is a disease of older adults. Efforts to intensify therapy along traditional avenues have failed to yield improved results. There remains significant clinical equipoise as to how to {"}induce{"} patients and whether or not 7 + 3-style regimens improve outcomes over low-dose cytarabine. What is certain is that even in those not receiving active therapy, AML is an exceptionally morbid disease. Diverse interventions are being explored in the management of older patients with AML and the currently available data will be reviewed.",
author = "Michael Martin and Abboud, {Camille N.}",
year = "2008",
month = "11",
day = "1",
doi = "10.1016/j.blre.2008.04.004",
language = "English (US)",
volume = "22",
pages = "311--320",
journal = "Blood Reviews",
issn = "0268-960X",
publisher = "Churchill Livingstone",
number = "6",

}

TY - JOUR

T1 - Induction therapy for elderly patients with acute myeloid leukemia

AU - Martin, Michael

AU - Abboud, Camille N.

PY - 2008/11/1

Y1 - 2008/11/1

N2 - Acute myeloid leukemia (AML) is a disease of older adults. Efforts to intensify therapy along traditional avenues have failed to yield improved results. There remains significant clinical equipoise as to how to "induce" patients and whether or not 7 + 3-style regimens improve outcomes over low-dose cytarabine. What is certain is that even in those not receiving active therapy, AML is an exceptionally morbid disease. Diverse interventions are being explored in the management of older patients with AML and the currently available data will be reviewed.

AB - Acute myeloid leukemia (AML) is a disease of older adults. Efforts to intensify therapy along traditional avenues have failed to yield improved results. There remains significant clinical equipoise as to how to "induce" patients and whether or not 7 + 3-style regimens improve outcomes over low-dose cytarabine. What is certain is that even in those not receiving active therapy, AML is an exceptionally morbid disease. Diverse interventions are being explored in the management of older patients with AML and the currently available data will be reviewed.

UR - http://www.scopus.com/inward/record.url?scp=54049150774&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=54049150774&partnerID=8YFLogxK

U2 - 10.1016/j.blre.2008.04.004

DO - 10.1016/j.blre.2008.04.004

M3 - Article

VL - 22

SP - 311

EP - 320

JO - Blood Reviews

JF - Blood Reviews

SN - 0268-960X

IS - 6

ER -