Ingibirovanie soevym ingibitorom tipa Baumana-Birk gidorliza élastina, kataliziruemogo élastazoǐ i katepsinom G iz leǐkotsitov cheloveka.

Translated title of the contribution: Inhibition of elastin hydrolysis, catalyzed by human leukocyte elastase and cathepsin G, by the Bowman-Birk type soy inhibitor

T. V. Tikhonova, I. P. Gladysheva, N. F. Kazanskaia, N. I. Larionova

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cathepsin G stimulates the hydrolysis of elastin from bovine neck ligament catalyzed by human leukocyte elastase. Stimulation factor depends on the ratio of the enzyme concentrations and ionic strength and equals 1.0-2.0. The classical Bowman-Birk inhibitor from soya retards strongly the hydrolysis of elastin catalyzed by leukocyte elastase, cathepsin G and the mixture of both. The inhibitory effect is practically unaffected by the adsorption of the enzymes on elastin, prolongation of the enzymatic reaction and ionic strength.

Original languageRussian
Pages (from-to)1739-1745
Number of pages7
JournalBiokhimiya
Volume59
Issue number11
StatePublished - Nov 1 1994

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Cathepsin G
Leukocyte Elastase
Elastin
Hydrolysis
Ionic strength
Ligaments
Enzymes
Adsorption

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

Tikhonova, T. V., Gladysheva, I. P., Kazanskaia, N. F., & Larionova, N. I. (1994). Ingibirovanie soevym ingibitorom tipa Baumana-Birk gidorliza élastina, kataliziruemogo élastazoǐ i katepsinom G iz leǐkotsitov cheloveka. Biokhimiya, 59(11), 1739-1745.

Ingibirovanie soevym ingibitorom tipa Baumana-Birk gidorliza élastina, kataliziruemogo élastazoǐ i katepsinom G iz leǐkotsitov cheloveka. / Tikhonova, T. V.; Gladysheva, I. P.; Kazanskaia, N. F.; Larionova, N. I.

In: Biokhimiya, Vol. 59, No. 11, 01.11.1994, p. 1739-1745.

Research output: Contribution to journalArticle

Tikhonova, TV, Gladysheva, IP, Kazanskaia, NF & Larionova, NI 1994, 'Ingibirovanie soevym ingibitorom tipa Baumana-Birk gidorliza élastina, kataliziruemogo élastazoǐ i katepsinom G iz leǐkotsitov cheloveka.', Biokhimiya, vol. 59, no. 11, pp. 1739-1745.
Tikhonova, T. V. ; Gladysheva, I. P. ; Kazanskaia, N. F. ; Larionova, N. I. / Ingibirovanie soevym ingibitorom tipa Baumana-Birk gidorliza élastina, kataliziruemogo élastazoǐ i katepsinom G iz leǐkotsitov cheloveka. In: Biokhimiya. 1994 ; Vol. 59, No. 11. pp. 1739-1745.
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