Inhibition of Streptococcus gordonii metabolic activity in biofilm by cranberry juice high-molecular-weight component

Jegdish Babu, Cohen Blair, Jacob Shiloah, Ofek Itzhak

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Previous studies demonstrated that a cranberry high-molecular-mass, nondialyzable material (NDM) can inhibit adhesion of numerous species of bacteria and prevents bacterial coaggregation of bacterial pairs. Bacterial coaggregation leads to plaque formation leading to biofilm development on surfaces of oral cavity. In the present study, we evaluated the effect of low concentrations of NDM on Streptococcus gordonii metabolic activity and biofilm formation on restorative dental surfaces. We found that the NDM selectively inhibited metabolic activity of S. gordonii, without affecting bacterial viability. Inhibiting the metabolic activity of bacteria in biofilm may benefit the health of the oral cavity.

Original languageEnglish (US)
Article number590384
JournalJournal of Biomedicine and Biotechnology
Volume2012
DOIs
StatePublished - Feb 3 2012

Fingerprint

Streptococcus gordonii
Vaccinium macrocarpon
Biofilms
Molecular Weight
Molecular weight
Mouth
Bacteria
Microbial Viability
Molecular mass
Insurance Benefits
Tooth
Adhesion
Health

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Medicine(all)
  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Health, Toxicology and Mutagenesis

Cite this

Inhibition of Streptococcus gordonii metabolic activity in biofilm by cranberry juice high-molecular-weight component. / Babu, Jegdish; Blair, Cohen; Shiloah, Jacob; Itzhak, Ofek.

In: Journal of Biomedicine and Biotechnology, Vol. 2012, 590384, 03.02.2012.

Research output: Contribution to journalArticle

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