Initial clinical experience with the Medtronic Micro Vascular Plug™ in transcatheter occlusion of PDAs in extremely premature infants

Shyam Sathanandam, Henri Justino, B. Rush Waller, Wolfgang Radtke, Athar M. Qureshi

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objectives: To describe the early multicenter, clinical experience with the Medtronic Micro Vascular Plug™ (MVP) for the occlusion of patent ductus arteriosus (PDA) in premature infants. Background: The MVP is a large diameter plug that can be delivered through a microcatheter for occlusion of abnormal blood vessels. Methods: A Retrospective review of PDA embolization procedures performed in two centers using the MVP was performed. Results: Fifteen premature infants underwent attempted PDA occlusion using the MVP. The gestational age and birth weight were 25.6 ± 2.5 weeks and 735 ± 251 g, respectively. The median weight and age at the time of the procedure were 1,210 g (700–3,500 g) and 4.5 weeks (2–12 weeks), respectively. Median procedure and fluoroscopy times were 45 and 6.5 min, respectively. The median radiation and contrast doses were 19.7 mGy and 2.4 mL/kg, respectively. Antegrade occlusion was successfully achieved in 13 patients <2 kg with only femoral venous access aided by echo guidance. The two patients >2 kg had arterial access and attempted retrograde occlusion; one of which was unsuccessful due to the PDA being short and wide. Complete closure was observed in 13 of 14 successful procedures (93%), with one patient having a small residual shunt that was not seen on follow-up. There were no complications related to the procedure or noted during follow-up (Median 11 months). Conclusions: The MVP is a new, large-diameter vascular embolization device that may be useful for the occlusion of PDA in extremely small, premature infants.

Original languageEnglish (US)
Pages (from-to)1051-1058
Number of pages8
JournalCatheterization and Cardiovascular Interventions
Volume89
Issue number6
DOIs
StatePublished - May 1 2017

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Extremely Premature Infants
Blood Vessels
Patent Ductus Arteriosus
Premature Infants
Fluoroscopy
Birth Weight
Gestational Age
Radiation
Weights and Measures
Equipment and Supplies

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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Initial clinical experience with the Medtronic Micro Vascular Plug™ in transcatheter occlusion of PDAs in extremely premature infants. / Sathanandam, Shyam; Justino, Henri; Waller, B. Rush; Radtke, Wolfgang; Qureshi, Athar M.

In: Catheterization and Cardiovascular Interventions, Vol. 89, No. 6, 01.05.2017, p. 1051-1058.

Research output: Contribution to journalArticle

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