Inpatient Outcomes for Gastrointestinal Bleeding Associated with Percutaneous Coronary Intervention

George Cholankeril, Menghan Hu, Rosann Cholankeril, Muhammad A. Khan, Chiran Gadiparthi, Eric R. Yoo, Ryan B. Perumpail, Satheesh Nair, Colin Howden

Research output: Contribution to journalArticle

Abstract

Goals: The goal of this study was to evaluate the impact of inpatient outcomes of gastrointestinal bleeding (GIB) related to percutaneous coronary intervention (PCI). Background: With all-cause mortality increasing in patients undergoing PCIs, outcomes for GIB associated with PCI may be adversely impacted. Study: Using the National Inpatient Sample (2007 to 2012), we performed a nested case-control study assessing inpatient outcomes including incidence and mortality for PCI-related GIB hospitalizations. Multivariate logistic regression analyses were performed to determine significant predictors for GIB incidence and mortality. Results: A total of 9332 (1.2%) of PCI hospitalizations were complicated by GIB with the age-adjusted incidence rate increasing 13% from 2007 (11.3 GIB per 1000 PCI) to 2012 (12.8). Patients ≥75 years of age experienced the steepest incline in GIB incidence, which increased 31% during the study period. Compared with non-GIB patients, mean length of stay (9.4 d vs. 3.3 d) and median cost of care ($29,236 vs. $17,913) was significantly higher. Significant demographic risk factors for GIB included older age and comorbid risk factors included gastritis or duodenitis, and Helicobacter pylori infection. In total, 1044 (11%) of GIB patients died during hospitalization with the GIB mortality rate increasing 30% from 2007 (95 deaths per 1000 GIB) to 2012 (123). Older age had the strongest association with inpatient mortality. Conclusions: Inpatient incidence and mortality for PCI-related GIB has been increasing particularly with a large increase in incidence among older patients. A multidisciplinary approach focused on risk-stratifying patients may improve preventable causes of GIB.

Original languageEnglish (US)
Pages (from-to)120-126
Number of pages7
JournalJournal of Clinical Gastroenterology
Volume53
Issue number2
DOIs
StatePublished - Feb 1 2019

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Percutaneous Coronary Intervention
Inpatients
Hemorrhage
Mortality
Incidence
Hospitalization
Duodenitis
Helicobacter Infections
Gastritis
Helicobacter pylori
Case-Control Studies
Length of Stay
Logistic Models

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Inpatient Outcomes for Gastrointestinal Bleeding Associated with Percutaneous Coronary Intervention. / Cholankeril, George; Hu, Menghan; Cholankeril, Rosann; Khan, Muhammad A.; Gadiparthi, Chiran; Yoo, Eric R.; Perumpail, Ryan B.; Nair, Satheesh; Howden, Colin.

In: Journal of Clinical Gastroenterology, Vol. 53, No. 2, 01.02.2019, p. 120-126.

Research output: Contribution to journalArticle

Cholankeril, G, Hu, M, Cholankeril, R, Khan, MA, Gadiparthi, C, Yoo, ER, Perumpail, RB, Nair, S & Howden, C 2019, 'Inpatient Outcomes for Gastrointestinal Bleeding Associated with Percutaneous Coronary Intervention', Journal of Clinical Gastroenterology, vol. 53, no. 2, pp. 120-126. https://doi.org/10.1097/MCG.0000000000000971
Cholankeril, George ; Hu, Menghan ; Cholankeril, Rosann ; Khan, Muhammad A. ; Gadiparthi, Chiran ; Yoo, Eric R. ; Perumpail, Ryan B. ; Nair, Satheesh ; Howden, Colin. / Inpatient Outcomes for Gastrointestinal Bleeding Associated with Percutaneous Coronary Intervention. In: Journal of Clinical Gastroenterology. 2019 ; Vol. 53, No. 2. pp. 120-126.
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AU - Yoo, Eric R.

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