Intestinal Permeability in Patients with Crohn's Disease and Their First‐Degree Relatives

Colin Howden, I. Gillanders, A. J. Morris, A. Duncan, B. Danesh, R. I. Russell

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective To measure small intestinal permeability in a group of patients with Crohn's disease in clinical remission and their apparently healthy first‐degree relatives. Methods: Administration of 51Cr‐labeled EDTA and subsequent measurement of its excretion in a 24‐h urine collection. Results: Excretion of 51Cr‐EDTA was not elevated in either the patients or in first‐degree relatives. Conclusion: Intestinal permeability to 5lCr‐EDTA is not raised in patients with Crohn's disease in clinical remission or in their healthy first‐degree relatives.

Original languageEnglish (US)
Pages (from-to)1175-1202
Number of pages28
JournalThe American journal of gastroenterology
Volume89
Issue number8
DOIs
StatePublished - Jan 1 1994
Externally publishedYes

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Crohn Disease
Permeability
Urine Specimen Collection
Edetic Acid

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Intestinal Permeability in Patients with Crohn's Disease and Their First‐Degree Relatives. / Howden, Colin; Gillanders, I.; Morris, A. J.; Duncan, A.; Danesh, B.; Russell, R. I.

In: The American journal of gastroenterology, Vol. 89, No. 8, 01.01.1994, p. 1175-1202.

Research output: Contribution to journalArticle

Howden, Colin ; Gillanders, I. ; Morris, A. J. ; Duncan, A. ; Danesh, B. ; Russell, R. I. / Intestinal Permeability in Patients with Crohn's Disease and Their First‐Degree Relatives. In: The American journal of gastroenterology. 1994 ; Vol. 89, No. 8. pp. 1175-1202.
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