Intravenous thrombolysis followed by intra-arterial thrombolysis and mechanical thrombectomy for the treatment of pediatric ischemic stroke

Georgios Tsivgoulis, Joseph A. Horton, Jayne M. Ness, Damon Patterson, Mary Brethour, Juan Carlos Abanses, Andrei Alexandrov

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Experience with systemic or selective local administration of thrombolytic agents in pediatric ischemic stroke is limited to sporadic case reports, since patients of age less than 18 years were systematically excluded from randomised controlled trials. We report a case of childhood IS attributable to the terminal internal carotid artery occlusion that was treated successfully with mechanical thrombectomy which followed unsuccessful attempts to recanalize the artery with intravenous and intra-arterial thrombolytics. Combined systemic and intra-arterial thrombolysis followed by mechanical thrombectomy can be feasible and may be considered as means of achieving reperfusion in pediatric ischemic stroke patients with persisting arterial occlusion.

Original languageEnglish (US)
Pages (from-to)151-153
Number of pages3
JournalJournal of the Neurological Sciences
Volume275
Issue number1-2
DOIs
StatePublished - Dec 15 2008

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Mechanical Thrombolysis
Thrombectomy
Stroke
Pediatrics
Fibrinolytic Agents
Internal Carotid Artery
Reperfusion
Randomized Controlled Trials
Arteries
Therapeutics

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

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Intravenous thrombolysis followed by intra-arterial thrombolysis and mechanical thrombectomy for the treatment of pediatric ischemic stroke. / Tsivgoulis, Georgios; Horton, Joseph A.; Ness, Jayne M.; Patterson, Damon; Brethour, Mary; Abanses, Juan Carlos; Alexandrov, Andrei.

In: Journal of the Neurological Sciences, Vol. 275, No. 1-2, 15.12.2008, p. 151-153.

Research output: Contribution to journalArticle

Tsivgoulis, Georgios ; Horton, Joseph A. ; Ness, Jayne M. ; Patterson, Damon ; Brethour, Mary ; Abanses, Juan Carlos ; Alexandrov, Andrei. / Intravenous thrombolysis followed by intra-arterial thrombolysis and mechanical thrombectomy for the treatment of pediatric ischemic stroke. In: Journal of the Neurological Sciences. 2008 ; Vol. 275, No. 1-2. pp. 151-153.
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