Invasive Mucormycosis in a patient with liver cirrhosis: Case report and review of the literature

Hussien Elsiesy, Mohamed Saad, Mahmoud Shorman, Samir Amr, Faisal Abaalkhail, Almoutaz Hashim, Waleed Al-Hamoudi, Mohamed Al Sebayel, Khalid Selim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Introduction: Cutaneous Mucormycosis is a rare opportunistic infection caused by Zygomycetes class of fungi that is often fatal, requiring aggressive local control as well as systemic therapy. Few cases of mucormycosis were described in patients with liver cirrhosis, mostly rhino-orbital. To our knowledge, only two cases of upper extremity involvement was reported in cirrhosis while a few cases were reported in the post-transplant setting. We report herein the third case of upper extremity mucor infection in the setting of liver cirrhosis. Case Presentation: We described a rare case of forearm infection originating in a traumatic intravenous access portal in a 25 year-old woman with liver cirrhosis secondary to autoimmune hepatitis. Discussion: She developed acute on chronic liver failure during the last trimester of pregnancy, which was terminated. Painful, erythematous lesion was noted on her right forearm in the area of intravenous access, which later became necrotic. Extensive debridement was done and histopathological examination confirmed the diagnosis of mucormycosis. The patient started on Amphotericin B. Her condition continued to deteriorate and ended up with above elbow amputation followed by right shoulder disarticulation. She died two days later due to multi-organ failure. In conclusion, forearm mucromycosis in liver cirrhosis can be fatal.

Original languageEnglish (US)
Article numbere10858
Number of pages1
JournalHepatitis Monthly
Volume13
Issue number8
DOIs
StatePublished - Aug 11 2013
Externally publishedYes

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Mucormycosis
Liver Cirrhosis
Forearm
Upper Extremity
Disarticulation
Mucor
Autoimmune Hepatitis
Opportunistic Infections
Third Pregnancy Trimester
Amphotericin B
Debridement
Elbow
Infection
Amputation
Fibrosis
Fungi
Transplants
Pregnancy
Skin

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Infectious Diseases

Cite this

Invasive Mucormycosis in a patient with liver cirrhosis : Case report and review of the literature. / Elsiesy, Hussien; Saad, Mohamed; Shorman, Mahmoud; Amr, Samir; Abaalkhail, Faisal; Hashim, Almoutaz; Al-Hamoudi, Waleed; Sebayel, Mohamed Al; Selim, Khalid.

In: Hepatitis Monthly, Vol. 13, No. 8, e10858, 11.08.2013.

Research output: Contribution to journalArticle

Elsiesy, H, Saad, M, Shorman, M, Amr, S, Abaalkhail, F, Hashim, A, Al-Hamoudi, W, Sebayel, MA & Selim, K 2013, 'Invasive Mucormycosis in a patient with liver cirrhosis: Case report and review of the literature', Hepatitis Monthly, vol. 13, no. 8, e10858. https://doi.org/10.5812/hepatmon.10858
Elsiesy, Hussien ; Saad, Mohamed ; Shorman, Mahmoud ; Amr, Samir ; Abaalkhail, Faisal ; Hashim, Almoutaz ; Al-Hamoudi, Waleed ; Sebayel, Mohamed Al ; Selim, Khalid. / Invasive Mucormycosis in a patient with liver cirrhosis : Case report and review of the literature. In: Hepatitis Monthly. 2013 ; Vol. 13, No. 8.
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