Involvement of hysteretic effects in the inhibition of carnitine palmitoyltransferase by malonyl-CoA

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Carnitine palmitoyltransferase in its normal mitochondrial environment behaves as a hysteretic enzyme, exhibiting slow changes in reaction rate after the addition of oleoyl-CoA or malonyl-CoA. Reaction rates become constant after a short time, but the sensitivity of the enzyme from fed rats to the inhibition by malonyl-CoA remains much greater than that of starved rats.

Original languageEnglish (US)
Pages (from-to)1015-1018
Number of pages4
JournalBiochemical Journal
Volume224
Issue number3
DOIs
StatePublished - Jan 1 1984

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Malonyl Coenzyme A
Carnitine O-Palmitoyltransferase
Reaction rates
Rats
Enzymes
oleoyl-coenzyme A

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Involvement of hysteretic effects in the inhibition of carnitine palmitoyltransferase by malonyl-CoA. / Cook, George.

In: Biochemical Journal, Vol. 224, No. 3, 01.01.1984, p. 1015-1018.

Research output: Contribution to journalArticle

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