Is Theophylline Use Justified in Acute Exacerbations of Asthma?

Timothy H. Self, Robert F. Ellis, Nabil Abou‐Shala, Naseem Amarshi

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Despite widespread use of theophylline in the hospital management of asthma, supportive data justifying its use are sparse. Clinical research in the 1980s has forced a serious new examination of the drug's role in acute exacerbations of asthma. Because of the morbidity, mortality, questionable value, and overall cost of theophylline therapy, this reevaluation is of particular importance. Enhanced knowledge of the value of treatment with intensive inhaled ß agonists, systemic glucocorticoids, and inhaled ipratropium should prompt elimination of the routine, initial use of theophylline in emergency room care of most asthmatics. Further research is necessary to justify the routine, initial use of the drug in hospitalized asthmatics. 1989 Pharmacotherapy Publications Inc.

Original languageEnglish (US)
Pages (from-to)260-266
Number of pages7
JournalPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
Volume9
Issue number4
DOIs
StatePublished - Jan 1 1989

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Theophylline
Asthma
Ipratropium
Emergency Medical Services
Research
Pharmaceutical Preparations
Glucocorticoids
Publications
Hospital Emergency Service
Morbidity
Costs and Cost Analysis
Drug Therapy
Mortality
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

Cite this

Is Theophylline Use Justified in Acute Exacerbations of Asthma? / Self, Timothy H.; Ellis, Robert F.; Abou‐Shala, Nabil; Amarshi, Naseem.

In: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Vol. 9, No. 4, 01.01.1989, p. 260-266.

Research output: Contribution to journalReview article

Self, Timothy H. ; Ellis, Robert F. ; Abou‐Shala, Nabil ; Amarshi, Naseem. / Is Theophylline Use Justified in Acute Exacerbations of Asthma?. In: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 1989 ; Vol. 9, No. 4. pp. 260-266.
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