Karolinska Institutet 200-year anniversary. Symposium on traumatic injuries in the nervous system: Injuries to the spinal cord and peripheral nervous system-injuries and repair, pain problems, lesions to brachial plexus

Mattias K. Sköld, Mikael Svensson, Jack Tsao, Thomas Hultgren, Thomas Landegren, Thomas Carlstedt, Staffan Cullheim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The Karolinska Institutet 200-year anniversary symposium on injuries to the spinal cord and peripheral nervous system gathered expertise in the spinal cord, spinal nerve, and peripheral nerve injury field spanning from molecular prerequisites for nerve regeneration to clinical methods in nerve repair and rehabilitation. The topics presented at the meeting covered findings on adult neural stem cells that when transplanted to the hypoglossal nucleus in the rat could integrate with its host and promote neuron survival. Studies on vascularization after intraspinal replantation of ventral nerve roots and microarray studies in ventral root replantation as a tool for mapping of biological patterns typical for neuronal regeneration were discussed. Different immune molecules in neurons and glia and their very specific roles in synapse plasticity after injury were presented. Novel strategies in repair of injured peripheral nerves with ethyl-cyanoacrylate adhesive showed functional recovery comparable to that of conventional epineural sutures. Various aspects on surgical techniques which are available to improve function of the limb, once the nerve regeneration after brachial plexus lesions and repair has reached its limit were presented. Moreover, neurogenic pain after amputation and its treatment with mirror therapy were shown to be followed by dramatic decrease in phantom limb pain. Finally clinical experiences on surgical techniques to repair avulsed spinal nerve root and the motoric as well as sensoric regain of function were presented.

Original languageEnglish (US)
Article numberArticle 29
JournalFrontiers in Neurology
VolumeMAY
DOIs
StatePublished - Dec 1 2011

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Nervous System Trauma
Brachial Plexus
Spinal Nerve Roots
Peripheral Nervous System
Anniversaries and Special Events
Spinal Cord
Nerve Regeneration
Replantation
Pain
Wounds and Injuries
Phantom Limb
Neurons
Peripheral Nerve Injuries
Spinal Nerves
Adult Stem Cells
Neural Stem Cells
Spinal Cord Injuries
Peripheral Nerves
Amputation
Neuroglia

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Karolinska Institutet 200-year anniversary. Symposium on traumatic injuries in the nervous system : Injuries to the spinal cord and peripheral nervous system-injuries and repair, pain problems, lesions to brachial plexus. / Sköld, Mattias K.; Svensson, Mikael; Tsao, Jack; Hultgren, Thomas; Landegren, Thomas; Carlstedt, Thomas; Cullheim, Staffan.

In: Frontiers in Neurology, Vol. MAY, Article 29, 01.12.2011.

Research output: Contribution to journalArticle

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