Lateralization of cerebral activation in auditory verbal and non-verbal memory tasks using magnetoencephalography

Joshua I. Breier, Panagiotis G. Simos, George Zouridakis, Andrew C. Papanicolaou

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

The magnetic flux normal to the scalp surface was measured with a whole-head neuromagnetometer while right-handed subjects (N = 15) were engaged in either an auditory word- or a tone-recognition task. Sources of the recorded magnetic fields were modeled as equivalent current dipoles at 4 ms intervals and the number of sources in the later portion of the magnetic response was used as an index of the degree of brain activation. Significantly more sources were found in the left as compared to the right hemisphere in the word but not the tone task on a group basis. On an individual basis, 13/15 subjects had more sources in the left as compared to the right hemisphere during the word task, while in the tone task 3/10 subjects showed this pattern. Sources of activity were found in the left superior and middle temporal gyri in all subjects with available MRI scans. Sources were also found in the supramarginal gyrus and in medial temporal areas, including the hippocampus, in the majority of cases. MEG appears to be a promising tool for detecting activity in cerebral areas specialized for language and memory function.

Original languageEnglish (US)
Pages (from-to)89-97
Number of pages9
JournalBrain Topography
Volume12
Issue number2
DOIs
StatePublished - Jan 1 1999

Fingerprint

Magnetoencephalography
Parietal Lobe
Temporal Lobe
Magnetic Fields
Scalp
Hippocampus
Language
Head
Magnetic Resonance Imaging
Brain
Recognition (Psychology)

All Science Journal Classification (ASJC) codes

  • Anatomy
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology

Cite this

Lateralization of cerebral activation in auditory verbal and non-verbal memory tasks using magnetoencephalography. / Breier, Joshua I.; Simos, Panagiotis G.; Zouridakis, George; Papanicolaou, Andrew C.

In: Brain Topography, Vol. 12, No. 2, 01.01.1999, p. 89-97.

Research output: Contribution to journalArticle

Breier, Joshua I. ; Simos, Panagiotis G. ; Zouridakis, George ; Papanicolaou, Andrew C. / Lateralization of cerebral activation in auditory verbal and non-verbal memory tasks using magnetoencephalography. In: Brain Topography. 1999 ; Vol. 12, No. 2. pp. 89-97.
@article{0aed87c954dd46adb6ed5813bbd2d3f9,
title = "Lateralization of cerebral activation in auditory verbal and non-verbal memory tasks using magnetoencephalography",
abstract = "The magnetic flux normal to the scalp surface was measured with a whole-head neuromagnetometer while right-handed subjects (N = 15) were engaged in either an auditory word- or a tone-recognition task. Sources of the recorded magnetic fields were modeled as equivalent current dipoles at 4 ms intervals and the number of sources in the later portion of the magnetic response was used as an index of the degree of brain activation. Significantly more sources were found in the left as compared to the right hemisphere in the word but not the tone task on a group basis. On an individual basis, 13/15 subjects had more sources in the left as compared to the right hemisphere during the word task, while in the tone task 3/10 subjects showed this pattern. Sources of activity were found in the left superior and middle temporal gyri in all subjects with available MRI scans. Sources were also found in the supramarginal gyrus and in medial temporal areas, including the hippocampus, in the majority of cases. MEG appears to be a promising tool for detecting activity in cerebral areas specialized for language and memory function.",
author = "Breier, {Joshua I.} and Simos, {Panagiotis G.} and George Zouridakis and Papanicolaou, {Andrew C.}",
year = "1999",
month = "1",
day = "1",
doi = "10.1023/A:1023458110869",
language = "English (US)",
volume = "12",
pages = "89--97",
journal = "Brain Topography",
issn = "0896-0267",
publisher = "Kluwer Academic/Human Sciences Press Inc.",
number = "2",

}

TY - JOUR

T1 - Lateralization of cerebral activation in auditory verbal and non-verbal memory tasks using magnetoencephalography

AU - Breier, Joshua I.

AU - Simos, Panagiotis G.

AU - Zouridakis, George

AU - Papanicolaou, Andrew C.

PY - 1999/1/1

Y1 - 1999/1/1

N2 - The magnetic flux normal to the scalp surface was measured with a whole-head neuromagnetometer while right-handed subjects (N = 15) were engaged in either an auditory word- or a tone-recognition task. Sources of the recorded magnetic fields were modeled as equivalent current dipoles at 4 ms intervals and the number of sources in the later portion of the magnetic response was used as an index of the degree of brain activation. Significantly more sources were found in the left as compared to the right hemisphere in the word but not the tone task on a group basis. On an individual basis, 13/15 subjects had more sources in the left as compared to the right hemisphere during the word task, while in the tone task 3/10 subjects showed this pattern. Sources of activity were found in the left superior and middle temporal gyri in all subjects with available MRI scans. Sources were also found in the supramarginal gyrus and in medial temporal areas, including the hippocampus, in the majority of cases. MEG appears to be a promising tool for detecting activity in cerebral areas specialized for language and memory function.

AB - The magnetic flux normal to the scalp surface was measured with a whole-head neuromagnetometer while right-handed subjects (N = 15) were engaged in either an auditory word- or a tone-recognition task. Sources of the recorded magnetic fields were modeled as equivalent current dipoles at 4 ms intervals and the number of sources in the later portion of the magnetic response was used as an index of the degree of brain activation. Significantly more sources were found in the left as compared to the right hemisphere in the word but not the tone task on a group basis. On an individual basis, 13/15 subjects had more sources in the left as compared to the right hemisphere during the word task, while in the tone task 3/10 subjects showed this pattern. Sources of activity were found in the left superior and middle temporal gyri in all subjects with available MRI scans. Sources were also found in the supramarginal gyrus and in medial temporal areas, including the hippocampus, in the majority of cases. MEG appears to be a promising tool for detecting activity in cerebral areas specialized for language and memory function.

UR - http://www.scopus.com/inward/record.url?scp=0033382341&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033382341&partnerID=8YFLogxK

U2 - 10.1023/A:1023458110869

DO - 10.1023/A:1023458110869

M3 - Article

VL - 12

SP - 89

EP - 97

JO - Brain Topography

JF - Brain Topography

SN - 0896-0267

IS - 2

ER -