Left ventricular noncompaction cardiomyopathy in Duchenne muscular dystrophy carriers

John J. Parent, Ryan A. Moore, Michael D. Taylor, Jeffrey Towbin, John Jefferies

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Duchenne and Becker muscular dystrophies are X-linked hereditary myopathies secondary to a dystrophinopathy resulting in progressive cardiomyopathy and heart failure. The most commonly associated cardiac involvements in these patients are dilated cardiomyopathy and conduction abnormalities; however, recent studies have shown a high prevalence of left ventricular noncompaction cardiomyopathy in patients with Duchenne muscular dystrophy. Furthermore, there is increasing awareness of cardiomyopathy in female heterozygous dystrophinopathy carriers. We report a case series of two dystrophinopathy carriers with the dilated form of left ventricular noncompaction cardiomyopathy, a newly identified association.<. Learning objective: Dystrophinopathy carriers can manifest cardiac disease in the form of cardiomyopathy. We present a novel finding of carriers who manifest their cardiomyopathy in the form of left ventricular noncompaction, dilated phenotype. This has been described previously in patients with Duchenne muscular dystrophy.>.

Original languageEnglish (US)
Pages (from-to)7-9
Number of pages3
JournalJournal of Cardiology Cases
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2015

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Duchenne Muscular Dystrophy
Cardiomyopathies
Dilated Cardiomyopathy
Muscular Diseases
Heart Failure

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Left ventricular noncompaction cardiomyopathy in Duchenne muscular dystrophy carriers. / Parent, John J.; Moore, Ryan A.; Taylor, Michael D.; Towbin, Jeffrey; Jefferies, John.

In: Journal of Cardiology Cases, Vol. 11, No. 1, 01.01.2015, p. 7-9.

Research output: Contribution to journalArticle

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