Lifestyle factors and incident mobility limitation in obese and non-obese older adults

Annemarie Koster, Brenda W.J.H. Penninx, Anne B. Newman, Marjolein Visser, Coen H. Van Gool, Tamara B. Harris, Jacques Th M. Van Eijk, Gertrudis I.J.M. Kempen, Jennifer S. Brach, Eleanor M. Simonsick, Denise K. Houston, Frances Tylavsky, Susan M. Rubin, Stephen B. Kritchevsky

Research output: Contribution to journalArticle

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Abstract

Objective: This study examines the association between incident mobility limitation and 4 lifestyle factors: smoking, alcohol intake, physical activity, and diet in well-functioning obese (n = 667) and non-obese (n = 2027) older adults. Research Methods and Procedures: Data were from men and women, 70 to 79 years of age from Pittsburgh, PA and Memphis, TN, participating in the Health, Aging and Body Composition (Health ABC) study. In addition to individual lifestyle practices, a high-risk lifestyle score (0 to 4) was calculated indicating the total number of unhealthy lifestyle practices per person. Mobility limitation was defined as reported difficulty walking 1/4 mile or climbing 10 steps during two consecutive semiannual assessments over 6.5 years. Results: In non-obese older persons, significant risk factors for incident mobility limitation after adjustment for socio-demographics and health-related variables were current and former smoking [hazard ratio (HR) = 1.51; 95% confidence interval (CI), 1.20 to 1.89; HR = 1.40; 95% CI, 1.12 to 1.74), former alcohol intake (HR = 1.30; 95% CI, 1.05 to 1.60), low and medium physical activity (HR = 1.78; 95% CI, 1.45 to 2.18; HR = 1.29, 95% CI, 1.07 to 1.54), and eating an unhealthy diet (HR = 1.57; 95% CI, 1.17 to 2.10). In the obese, only low physical activity was associated with a significantly increased risk of mobility limitation (HR = 1.44; 95% CI, 1.08 to 1.92). Having two or more unhealthy lifestyle factors was a strong predictor of mobility limitation in the non-obese only (HR = 1.98; 95% CI, 1.61 to 2.43). Overall, obese persons had a significantly higher risk of mobility limitation compared with non-obese persons, independent of lifestyle factors (HR = 1.73; 95% CI, 1.52 to 1.96). Conclusions: These results underscore the importance of a healthy lifestyle for maintaining function among non-obese older adults. However, a healthy lifestyle cannot overcome the effect of obesity in obese older adults; this stresses the importance of preventing obesity to protect against mobility loss in older persons.

Original languageEnglish (US)
Pages (from-to)3122-3132
Number of pages11
JournalObesity
Volume15
Issue number12
DOIs
StatePublished - Dec 1 2007

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Mobility Limitation
Life Style
Confidence Intervals
Exercise
Obesity
Smoking
Alcohols
Diet
Health
Body Composition
Eating
Demography

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

Cite this

Koster, A., Penninx, B. W. J. H., Newman, A. B., Visser, M., Van Gool, C. H., Harris, T. B., ... Kritchevsky, S. B. (2007). Lifestyle factors and incident mobility limitation in obese and non-obese older adults. Obesity, 15(12), 3122-3132. https://doi.org/10.1038/oby.2007.372

Lifestyle factors and incident mobility limitation in obese and non-obese older adults. / Koster, Annemarie; Penninx, Brenda W.J.H.; Newman, Anne B.; Visser, Marjolein; Van Gool, Coen H.; Harris, Tamara B.; Van Eijk, Jacques Th M.; Kempen, Gertrudis I.J.M.; Brach, Jennifer S.; Simonsick, Eleanor M.; Houston, Denise K.; Tylavsky, Frances; Rubin, Susan M.; Kritchevsky, Stephen B.

In: Obesity, Vol. 15, No. 12, 01.12.2007, p. 3122-3132.

Research output: Contribution to journalArticle

Koster, A, Penninx, BWJH, Newman, AB, Visser, M, Van Gool, CH, Harris, TB, Van Eijk, JTM, Kempen, GIJM, Brach, JS, Simonsick, EM, Houston, DK, Tylavsky, F, Rubin, SM & Kritchevsky, SB 2007, 'Lifestyle factors and incident mobility limitation in obese and non-obese older adults', Obesity, vol. 15, no. 12, pp. 3122-3132. https://doi.org/10.1038/oby.2007.372
Koster A, Penninx BWJH, Newman AB, Visser M, Van Gool CH, Harris TB et al. Lifestyle factors and incident mobility limitation in obese and non-obese older adults. Obesity. 2007 Dec 1;15(12):3122-3132. https://doi.org/10.1038/oby.2007.372
Koster, Annemarie ; Penninx, Brenda W.J.H. ; Newman, Anne B. ; Visser, Marjolein ; Van Gool, Coen H. ; Harris, Tamara B. ; Van Eijk, Jacques Th M. ; Kempen, Gertrudis I.J.M. ; Brach, Jennifer S. ; Simonsick, Eleanor M. ; Houston, Denise K. ; Tylavsky, Frances ; Rubin, Susan M. ; Kritchevsky, Stephen B. / Lifestyle factors and incident mobility limitation in obese and non-obese older adults. In: Obesity. 2007 ; Vol. 15, No. 12. pp. 3122-3132.
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abstract = "Objective: This study examines the association between incident mobility limitation and 4 lifestyle factors: smoking, alcohol intake, physical activity, and diet in well-functioning obese (n = 667) and non-obese (n = 2027) older adults. Research Methods and Procedures: Data were from men and women, 70 to 79 years of age from Pittsburgh, PA and Memphis, TN, participating in the Health, Aging and Body Composition (Health ABC) study. In addition to individual lifestyle practices, a high-risk lifestyle score (0 to 4) was calculated indicating the total number of unhealthy lifestyle practices per person. Mobility limitation was defined as reported difficulty walking 1/4 mile or climbing 10 steps during two consecutive semiannual assessments over 6.5 years. Results: In non-obese older persons, significant risk factors for incident mobility limitation after adjustment for socio-demographics and health-related variables were current and former smoking [hazard ratio (HR) = 1.51; 95{\%} confidence interval (CI), 1.20 to 1.89; HR = 1.40; 95{\%} CI, 1.12 to 1.74), former alcohol intake (HR = 1.30; 95{\%} CI, 1.05 to 1.60), low and medium physical activity (HR = 1.78; 95{\%} CI, 1.45 to 2.18; HR = 1.29, 95{\%} CI, 1.07 to 1.54), and eating an unhealthy diet (HR = 1.57; 95{\%} CI, 1.17 to 2.10). In the obese, only low physical activity was associated with a significantly increased risk of mobility limitation (HR = 1.44; 95{\%} CI, 1.08 to 1.92). Having two or more unhealthy lifestyle factors was a strong predictor of mobility limitation in the non-obese only (HR = 1.98; 95{\%} CI, 1.61 to 2.43). Overall, obese persons had a significantly higher risk of mobility limitation compared with non-obese persons, independent of lifestyle factors (HR = 1.73; 95{\%} CI, 1.52 to 1.96). Conclusions: These results underscore the importance of a healthy lifestyle for maintaining function among non-obese older adults. However, a healthy lifestyle cannot overcome the effect of obesity in obese older adults; this stresses the importance of preventing obesity to protect against mobility loss in older persons.",
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T1 - Lifestyle factors and incident mobility limitation in obese and non-obese older adults

AU - Koster, Annemarie

AU - Penninx, Brenda W.J.H.

AU - Newman, Anne B.

AU - Visser, Marjolein

AU - Van Gool, Coen H.

AU - Harris, Tamara B.

AU - Van Eijk, Jacques Th M.

AU - Kempen, Gertrudis I.J.M.

AU - Brach, Jennifer S.

AU - Simonsick, Eleanor M.

AU - Houston, Denise K.

AU - Tylavsky, Frances

AU - Rubin, Susan M.

AU - Kritchevsky, Stephen B.

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N2 - Objective: This study examines the association between incident mobility limitation and 4 lifestyle factors: smoking, alcohol intake, physical activity, and diet in well-functioning obese (n = 667) and non-obese (n = 2027) older adults. Research Methods and Procedures: Data were from men and women, 70 to 79 years of age from Pittsburgh, PA and Memphis, TN, participating in the Health, Aging and Body Composition (Health ABC) study. In addition to individual lifestyle practices, a high-risk lifestyle score (0 to 4) was calculated indicating the total number of unhealthy lifestyle practices per person. Mobility limitation was defined as reported difficulty walking 1/4 mile or climbing 10 steps during two consecutive semiannual assessments over 6.5 years. Results: In non-obese older persons, significant risk factors for incident mobility limitation after adjustment for socio-demographics and health-related variables were current and former smoking [hazard ratio (HR) = 1.51; 95% confidence interval (CI), 1.20 to 1.89; HR = 1.40; 95% CI, 1.12 to 1.74), former alcohol intake (HR = 1.30; 95% CI, 1.05 to 1.60), low and medium physical activity (HR = 1.78; 95% CI, 1.45 to 2.18; HR = 1.29, 95% CI, 1.07 to 1.54), and eating an unhealthy diet (HR = 1.57; 95% CI, 1.17 to 2.10). In the obese, only low physical activity was associated with a significantly increased risk of mobility limitation (HR = 1.44; 95% CI, 1.08 to 1.92). Having two or more unhealthy lifestyle factors was a strong predictor of mobility limitation in the non-obese only (HR = 1.98; 95% CI, 1.61 to 2.43). Overall, obese persons had a significantly higher risk of mobility limitation compared with non-obese persons, independent of lifestyle factors (HR = 1.73; 95% CI, 1.52 to 1.96). Conclusions: These results underscore the importance of a healthy lifestyle for maintaining function among non-obese older adults. However, a healthy lifestyle cannot overcome the effect of obesity in obese older adults; this stresses the importance of preventing obesity to protect against mobility loss in older persons.

AB - Objective: This study examines the association between incident mobility limitation and 4 lifestyle factors: smoking, alcohol intake, physical activity, and diet in well-functioning obese (n = 667) and non-obese (n = 2027) older adults. Research Methods and Procedures: Data were from men and women, 70 to 79 years of age from Pittsburgh, PA and Memphis, TN, participating in the Health, Aging and Body Composition (Health ABC) study. In addition to individual lifestyle practices, a high-risk lifestyle score (0 to 4) was calculated indicating the total number of unhealthy lifestyle practices per person. Mobility limitation was defined as reported difficulty walking 1/4 mile or climbing 10 steps during two consecutive semiannual assessments over 6.5 years. Results: In non-obese older persons, significant risk factors for incident mobility limitation after adjustment for socio-demographics and health-related variables were current and former smoking [hazard ratio (HR) = 1.51; 95% confidence interval (CI), 1.20 to 1.89; HR = 1.40; 95% CI, 1.12 to 1.74), former alcohol intake (HR = 1.30; 95% CI, 1.05 to 1.60), low and medium physical activity (HR = 1.78; 95% CI, 1.45 to 2.18; HR = 1.29, 95% CI, 1.07 to 1.54), and eating an unhealthy diet (HR = 1.57; 95% CI, 1.17 to 2.10). In the obese, only low physical activity was associated with a significantly increased risk of mobility limitation (HR = 1.44; 95% CI, 1.08 to 1.92). Having two or more unhealthy lifestyle factors was a strong predictor of mobility limitation in the non-obese only (HR = 1.98; 95% CI, 1.61 to 2.43). Overall, obese persons had a significantly higher risk of mobility limitation compared with non-obese persons, independent of lifestyle factors (HR = 1.73; 95% CI, 1.52 to 1.96). Conclusions: These results underscore the importance of a healthy lifestyle for maintaining function among non-obese older adults. However, a healthy lifestyle cannot overcome the effect of obesity in obese older adults; this stresses the importance of preventing obesity to protect against mobility loss in older persons.

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