LIPOSARCOMA of the head and neck

the university of texas M. D. anderson cancer center experience

Erica C. Davis, Matthew Ballo, Mario A. Luna, Shreyakumar R. Patel, Dianna B. Roberts, Xiaolin Nong, Erich M. Sturgis

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Background. Our aim was to review our experience with liposarcoma of the head and neck region. Methods. This is a retrospective case series at a comprehensive cancer center (1945-2005). Results. Of 30 patients, 10 (33%) were initially misdiagnosed. Local recurrences were common (overall rate = 53%), and 4 patients (13%) developed distant metastases. Decreased crude disease-specific survival rates were significantly associated with recurrence (especially distant recurrence [0%]), age less than 38 years (40%), and pleomorphic subtype (45%); however, in Kaplan-Meier analyses, only larger tumor size, negative margins, round cell subtype, and pleomorphic subtype were associated with significantly decreased disease-specific survival (log-rank test p = .048, .041, .021, and .012, respectively). Conclusions. Based on this limited experience and existing literature, we continue to recommend surgery with negative margins as the treatment of choice and that adjuvant therapies should be considered in patients with high-grade histology, large tumors, positive margins, or certain subsites.

Original languageEnglish (US)
Pages (from-to)28-36
Number of pages9
JournalHead and Neck
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2009

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Neck
Head
Recurrence
Liposarcoma
Neoplasms
Kaplan-Meier Estimate
Diagnostic Errors
Histology
Survival Rate
Neoplasm Metastasis
Survival
Therapeutics

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Davis, E. C., Ballo, M., Luna, M. A., Patel, S. R., Roberts, D. B., Nong, X., & Sturgis, E. M. (2009). LIPOSARCOMA of the head and neck: the university of texas M. D. anderson cancer center experience. Head and Neck, 31(1), 28-36. https://doi.org/10.1002/hed.20923

LIPOSARCOMA of the head and neck : the university of texas M. D. anderson cancer center experience. / Davis, Erica C.; Ballo, Matthew; Luna, Mario A.; Patel, Shreyakumar R.; Roberts, Dianna B.; Nong, Xiaolin; Sturgis, Erich M.

In: Head and Neck, Vol. 31, No. 1, 01.01.2009, p. 28-36.

Research output: Contribution to journalArticle

Davis, EC, Ballo, M, Luna, MA, Patel, SR, Roberts, DB, Nong, X & Sturgis, EM 2009, 'LIPOSARCOMA of the head and neck: the university of texas M. D. anderson cancer center experience', Head and Neck, vol. 31, no. 1, pp. 28-36. https://doi.org/10.1002/hed.20923
Davis, Erica C. ; Ballo, Matthew ; Luna, Mario A. ; Patel, Shreyakumar R. ; Roberts, Dianna B. ; Nong, Xiaolin ; Sturgis, Erich M. / LIPOSARCOMA of the head and neck : the university of texas M. D. anderson cancer center experience. In: Head and Neck. 2009 ; Vol. 31, No. 1. pp. 28-36.
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