Long chain polyunsaturated fatty acid supplementation in infancy increases length- and weight-for-age but not BMI to 6 years when controlling for effects of maternal smoking

L. M. Currie, Elizabeth Tolley, J. M. Thodosoff, E. H. Kerling, D. K. Sullivan, J. Colombo, S. E. Carlson

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Long chain polyunsaturated fatty acids (LCPUFA) are added to infant formula but their effect on long-term growth of children is under studied. We evaluated the effects of feeding LCPUFA-supplemented formula (n=54) compared to control formula (n=15) throughout infancy on growth from birth-6 years. Growth was described using separate models developed with the MIXED procedure of SAS® that included maternal smoking history and gender. Compared to children fed control formula, children who consumed LCPUFA supplemented formula had higher length-/stature-/and weight-for-age percentiles but not body mass index (BMI) percentile from birth to 6 years. Maternal smoking predicted lower stature (2-6 years), higher weight-for-length (birth-18 months) and BMI percentile (2-6 years) independent of LCPUFA effects. Gender interacted with the effect of LCPUFA on stature, and the relationship between smoking and BMI, with a larger effect for boys. Energy intake did not explain growth differences. A relatively small control sample is a limitation.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalProstaglandins Leukotrienes and Essential Fatty Acids
Volume98
DOIs
StatePublished - Jul 1 2015

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Unsaturated Fatty Acids
Body Mass Index
Smoking
Mothers
Weights and Measures
Growth
Parturition
Infant Formula
Energy Intake
Birth Weight
History

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry
  • Cell Biology

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Long chain polyunsaturated fatty acid supplementation in infancy increases length- and weight-for-age but not BMI to 6 years when controlling for effects of maternal smoking. / Currie, L. M.; Tolley, Elizabeth; Thodosoff, J. M.; Kerling, E. H.; Sullivan, D. K.; Colombo, J.; Carlson, S. E.

In: Prostaglandins Leukotrienes and Essential Fatty Acids, Vol. 98, 01.07.2015, p. 1-6.

Research output: Contribution to journalArticle

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