Magnetic resonance imaging detection of mesial temporal sclerosis in children

Yu Tze Ng, Amy L. McGregor, James Wheless

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The objective of this study was to investigate the prevalence and clinical characteristics of mesial temporal sclerosis as diagnosed by brain magnetic resonance imaging in children. A total of 390 consecutive brain magnetic resonance imaging studies in children were reviewed for evidence of mesial temporal sclerosis. Subsequently, the magnetic resonance imaging scans and charts of patients with mesial temporal sclerosis were reviewed and their clinical details were evaluated. The magnetic resonance imaging studies had been performed for multiple indications, including seizures, headache, and developmental problems. In children, the prevalence of mesial temporal sclerosis among all brain magnetic resonance imaging studies was 3.1% (12 of 390 studies) and 12.1% (12 of 99 studies) among all brain magnetic resonance imaging studies performed for seizures. These children all presented with a history of seizure disorder, often had other medical problems, and histopathology (when available) nearly always (5 of 6 patients) confirmed their magnetic resonance imaging diagnosis of mesial temporal sclerosis. The prevalence of mesial temporal sclerosis is low among all pediatric patients who had magnetic resonance imaging brain studies. All our mesial temporal sclerosis patients had clinical seizures; i.e., it was never an "incidental finding". Children with mesial temporal sclerosis often had comorbid conditions, and the diagnosis of mesial temporal sclerosis made by magnetic resonance imaging was accurate when compared with the available histopathology.

Original languageEnglish (US)
Pages (from-to)81-85
Number of pages5
JournalPediatric Neurology
Volume30
Issue number2
DOIs
StatePublished - Jan 1 2004
Externally publishedYes

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Sclerosis
Magnetic Resonance Imaging
Brain
Seizures
Incidental Findings
Headache
Epilepsy
Pediatrics

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

Cite this

Magnetic resonance imaging detection of mesial temporal sclerosis in children. / Ng, Yu Tze; McGregor, Amy L.; Wheless, James.

In: Pediatric Neurology, Vol. 30, No. 2, 01.01.2004, p. 81-85.

Research output: Contribution to journalArticle

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