Mandated Venous Thromboembolism Prophylaxis. Possible Adverse Outcomes

Wendy M. Novicoff, Thomas E. Brown, Quanjun Cui, William Mihalko, Harris S. Slone, Khaled J. Saleh

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The purpose of this study was to assess the prevalence and seriousness of adverse outcomes owing to mandatory venous thromboembolism (VTE) prophylaxis. A retrospective study of administrative claims data was conducted to look at the rate of VTEs and other complications in patients undergoing hip and knee arthroplasty. Additional analysis was done to determine whether patient characteristics could explain findings. Although rates of VTE remain unchanged from 2003 to 2007, the rate of immediate postprocedure hematoma, seroma, and hemorrhage went from 1.4% in 2003 to 9.6% in 2006. Return to a more conservative prophylaxis approach resulted in a marked decrease in rates of significant bleeding events. Although preventing VTEs is an important quality concern, mandating prophylaxis for all patients could have unintended adverse outcomes. These guidelines might need to be reevaluated for hip and knee arthroplasty patients.

Original languageEnglish (US)
Pages (from-to)15-19
Number of pages5
JournalJournal of Arthroplasty
Volume23
Issue number6 SUPPL.
DOIs
StatePublished - Sep 1 2008

Fingerprint

Venous Thromboembolism
Knee Replacement Arthroplasties
Hip
Hemorrhage
Seroma
Hematoma
Retrospective Studies
Guidelines

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine

Cite this

Novicoff, W. M., Brown, T. E., Cui, Q., Mihalko, W., Slone, H. S., & Saleh, K. J. (2008). Mandated Venous Thromboembolism Prophylaxis. Possible Adverse Outcomes. Journal of Arthroplasty, 23(6 SUPPL.), 15-19. https://doi.org/10.1016/j.arth.2008.04.014

Mandated Venous Thromboembolism Prophylaxis. Possible Adverse Outcomes. / Novicoff, Wendy M.; Brown, Thomas E.; Cui, Quanjun; Mihalko, William; Slone, Harris S.; Saleh, Khaled J.

In: Journal of Arthroplasty, Vol. 23, No. 6 SUPPL., 01.09.2008, p. 15-19.

Research output: Contribution to journalArticle

Novicoff, WM, Brown, TE, Cui, Q, Mihalko, W, Slone, HS & Saleh, KJ 2008, 'Mandated Venous Thromboembolism Prophylaxis. Possible Adverse Outcomes', Journal of Arthroplasty, vol. 23, no. 6 SUPPL., pp. 15-19. https://doi.org/10.1016/j.arth.2008.04.014
Novicoff, Wendy M. ; Brown, Thomas E. ; Cui, Quanjun ; Mihalko, William ; Slone, Harris S. ; Saleh, Khaled J. / Mandated Venous Thromboembolism Prophylaxis. Possible Adverse Outcomes. In: Journal of Arthroplasty. 2008 ; Vol. 23, No. 6 SUPPL. pp. 15-19.
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