Mapping of expressive language cortex using magnetic source imaging

Eduardo M. Castillo, Panagiotis G. Simos, Vijay Venkataraman, Joshua I. Breier, James Wheless, Andrew Papanicolaou

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The accurate localization of primary language cortex is one of the goals in the evaluation of brain surgery candidates. In this paper we describe the localization of expressive language cortex using magnetic source imaging (MSI) in a patient with refractory epilepsy caused by a tumor affecting the left inferior frontal gyrus. The magnetoencephalographic recordings during an expressive language task were co-registered with a magnetic resonance imaging (MRI) scan obtained after subdural grid placement and provided a cluster of sources of brain activation in the vicinity of the lesion. This map of expressive language provided by MSI was verified with electrocortical stimulation before the operation. No speech problems were reported in our patient after the resection of the lesion, suggesting that MSI is an accurate non-invasive method for the pre-surgical mapping of expressive language in cases where there is clear functional risk during tumor resection.

Original languageEnglish (US)
Pages (from-to)419-422
Number of pages4
JournalNeurocase
Volume7
Issue number5
DOIs
StatePublished - Dec 1 2001

Fingerprint

Language
Brain
Prefrontal Cortex
Epilepsy
Neoplasms
Magnetic Resonance Imaging
Expressive Language
Cortex
Imaging
Lesion
Localization

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Cite this

Castillo, E. M., Simos, P. G., Venkataraman, V., Breier, J. I., Wheless, J., & Papanicolaou, A. (2001). Mapping of expressive language cortex using magnetic source imaging. Neurocase, 7(5), 419-422. https://doi.org/10.1076/neur.7.5.419.16249

Mapping of expressive language cortex using magnetic source imaging. / Castillo, Eduardo M.; Simos, Panagiotis G.; Venkataraman, Vijay; Breier, Joshua I.; Wheless, James; Papanicolaou, Andrew.

In: Neurocase, Vol. 7, No. 5, 01.12.2001, p. 419-422.

Research output: Contribution to journalArticle

Castillo, EM, Simos, PG, Venkataraman, V, Breier, JI, Wheless, J & Papanicolaou, A 2001, 'Mapping of expressive language cortex using magnetic source imaging', Neurocase, vol. 7, no. 5, pp. 419-422. https://doi.org/10.1076/neur.7.5.419.16249
Castillo EM, Simos PG, Venkataraman V, Breier JI, Wheless J, Papanicolaou A. Mapping of expressive language cortex using magnetic source imaging. Neurocase. 2001 Dec 1;7(5):419-422. https://doi.org/10.1076/neur.7.5.419.16249
Castillo, Eduardo M. ; Simos, Panagiotis G. ; Venkataraman, Vijay ; Breier, Joshua I. ; Wheless, James ; Papanicolaou, Andrew. / Mapping of expressive language cortex using magnetic source imaging. In: Neurocase. 2001 ; Vol. 7, No. 5. pp. 419-422.
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