Massive hepatic artery atherosclerosis of an otherwise suitable donor liver

A case report

Daniel Maluf, B. D. Clark, A. H. Cotterell, M. P. Posner, R. A. Fisher

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Most of the few reports about hepatic artery disease found in the literature describe hepatic artery aneurysms or hepatic artery calcifications. Atherosclerosis of the hepatic artery is not commonly evaluated during deceased donor liver procurement. Herein we present a case of a stable 47-year-old Caucasian female donor whose liver function tests were within normal limits and a liver biopsy showed less than 5% steatosis. The liver when received at our center appeared grossly unremarkable. Back-table evaluation showed a complete occlusion of the trunk of the proper hepatic artery. The pathology report revealed hepatic occlusion due to arterial atherosclerosis. Transplantation was canceled, and the liver was used for isolated hepatocyte perfusion, revealing <25% hepatocyte viability. Hepatic artery atherosclerosis and patency need to be evaluated at the time of procurement to prevent recipient morbidity due to anesthetic induction, or initiation of a recipient abdominal incision prior to declining the liver graft for this rare finding.

Original languageEnglish (US)
Pages (from-to)1438-1441
Number of pages4
JournalTransplantation Proceedings
Volume36
Issue number5
DOIs
StatePublished - Jun 1 2004
Externally publishedYes

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Hepatic Artery
Atherosclerosis
Liver
Hepatocytes
Liver Function Tests
Aneurysm
Anesthetics
Perfusion
Transplantation
Pathology
Morbidity
Transplants
Biopsy

All Science Journal Classification (ASJC) codes

  • Surgery
  • Transplantation

Cite this

Massive hepatic artery atherosclerosis of an otherwise suitable donor liver : A case report. / Maluf, Daniel; Clark, B. D.; Cotterell, A. H.; Posner, M. P.; Fisher, R. A.

In: Transplantation Proceedings, Vol. 36, No. 5, 01.06.2004, p. 1438-1441.

Research output: Contribution to journalArticle

Maluf, Daniel ; Clark, B. D. ; Cotterell, A. H. ; Posner, M. P. ; Fisher, R. A. / Massive hepatic artery atherosclerosis of an otherwise suitable donor liver : A case report. In: Transplantation Proceedings. 2004 ; Vol. 36, No. 5. pp. 1438-1441.
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