Maturation of the heart

D. J. Fisher, Jeffrey Towbin

Research output: Contribution to journalReview article

18 Citations (Scopus)

Abstract

The transitions from fetal to newborn to adult previously have been associated with a progressive increase in myocardial contractile function. This review documents recent information regarding the subcellular basis. This includes the maturation of the ion pumps of the sarcoplasmic reticulum and the sarcolemma that regulate cytosolic calcium concentrations, as well as the molecular factors that regulate the maturation of the myofibrillar proteins that transduce the combination of calcium and chemical energy into the mechanical energy necessary for cardiac contraction.

Original languageEnglish (US)
Pages (from-to)421-446
Number of pages26
JournalClinics in Perinatology
Volume15
Issue number3
StatePublished - Jan 1 1988

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Ion Pumps
Calcium
Sarcolemma
Sarcoplasmic Reticulum
Proteins

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Fisher, D. J., & Towbin, J. (1988). Maturation of the heart. Clinics in Perinatology, 15(3), 421-446.

Maturation of the heart. / Fisher, D. J.; Towbin, Jeffrey.

In: Clinics in Perinatology, Vol. 15, No. 3, 01.01.1988, p. 421-446.

Research output: Contribution to journalReview article

Fisher, DJ & Towbin, J 1988, 'Maturation of the heart', Clinics in Perinatology, vol. 15, no. 3, pp. 421-446.
Fisher DJ, Towbin J. Maturation of the heart. Clinics in Perinatology. 1988 Jan 1;15(3):421-446.
Fisher, D. J. ; Towbin, Jeffrey. / Maturation of the heart. In: Clinics in Perinatology. 1988 ; Vol. 15, No. 3. pp. 421-446.
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