Medical management and strategies to prevent coronary artery disease in patients with type 2 diabetes mellitus

Mae Sheikh-Ali, Prafull Raheja, Nancy Hart

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM) is associated with increased immediate and long-term mortality compared with patients without T2DM. The amplified incidence of CAD stems partly from the aggregation of multiple risk factors, such as obesity, dyslipidemia, and hypertension, which occur in this population. In addition, there appear to be increased forces at play at the molecular and vascular levels in these individuals, which is evidenced by the increased thrombosis and inflammation that is seen in those with diabetic atherosclerosis. Hence, there is a growing need to emphasize early and vigilant risk factor management in patients with T2DM to help reduce their burden of cardiovascular-related mortality. In this article, we review the primary and secondary prevention measures as well as the management of CAD in patients with T2DM.

Original languageEnglish (US)
Pages (from-to)17-33
Number of pages17
JournalPostgraduate Medicine
Volume125
Issue number1
DOIs
StatePublished - Jan 1 2013
Externally publishedYes

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Type 2 Diabetes Mellitus
Coronary Artery Disease
Mortality
Risk Management
Primary Prevention
Dyslipidemias
Secondary Prevention
Blood Vessels
Atherosclerosis
Thrombosis
Obesity
Hypertension
Inflammation
Incidence
Population

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Medical management and strategies to prevent coronary artery disease in patients with type 2 diabetes mellitus. / Sheikh-Ali, Mae; Raheja, Prafull; Hart, Nancy.

In: Postgraduate Medicine, Vol. 125, No. 1, 01.01.2013, p. 17-33.

Research output: Contribution to journalArticle

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