Medication exposure in pregnancy risk evaluation program

Susan E. Andrade, Robert Davis, T. Craig Cheetham, William O. Cooper, De Kun Li, Thushi Amini, Sarah J. Beaton, Sascha Dublin, Tarek A. Hammad, Pamala A. Pawloski, Marsha A. Raebel, David H. Smith, Judy A. Staffa, Sengwee Toh, Inna Dashevsky, Katherine Haffenreffer, Kimberly Lane, Richard Platt, Pamela E. Scott

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

To describe a program to study medication safety in pregnancy, the Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP). MEPREP is a multisite collaborative research program developed to enable the conduct of studies of medication use and outcomes in pregnancy. Collaborators include the U.S. Food and Drug Administration and researchers at the HMO Research Network, Kaiser Permanente Northern and Southern California, and Vanderbilt University. Datasets have been created at each site linking healthcare data for women delivering an infant between January 1, 2001 and December 31, 2008 and infants born to these women. Standardized data files include maternal and infant characteristics, medication use, and medical care at 11 health plans within 9 states; birth certificate data were obtained from the state departments of public health. MEPREP currently involves more than 20 medication safety researchers and includes data for 1,221,156 children delivered to 933,917 mothers. Current studies include evaluations of the prevalence and patterns of use of specific medications and a validation study of data elements in the administrative and birth certificate data files. MEPREP can support multiple studies by providing information on a large, ethnically and geographically diverse population. This partnership combines clinical and research expertise and data resources to enable the evaluation of outcomes associated with medication use during pregnancy.

Original languageEnglish (US)
Pages (from-to)1349-1354
Number of pages6
JournalMaternal and child health journal
Volume16
Issue number7
DOIs
StatePublished - Oct 1 2012

Fingerprint

Program Evaluation
Pregnancy
Birth Certificates
Information Storage and Retrieval
Research
Mothers
Research Personnel
Safety
Health Maintenance Organizations
Validation Studies
United States Food and Drug Administration
Pregnancy Outcome
Public Health
Delivery of Health Care
Health
Population

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology
  • Public Health, Environmental and Occupational Health

Cite this

Andrade, S. E., Davis, R., Cheetham, T. C., Cooper, W. O., Li, D. K., Amini, T., ... Scott, P. E. (2012). Medication exposure in pregnancy risk evaluation program. Maternal and child health journal, 16(7), 1349-1354. https://doi.org/10.1007/s10995-011-0902-x

Medication exposure in pregnancy risk evaluation program. / Andrade, Susan E.; Davis, Robert; Cheetham, T. Craig; Cooper, William O.; Li, De Kun; Amini, Thushi; Beaton, Sarah J.; Dublin, Sascha; Hammad, Tarek A.; Pawloski, Pamala A.; Raebel, Marsha A.; Smith, David H.; Staffa, Judy A.; Toh, Sengwee; Dashevsky, Inna; Haffenreffer, Katherine; Lane, Kimberly; Platt, Richard; Scott, Pamela E.

In: Maternal and child health journal, Vol. 16, No. 7, 01.10.2012, p. 1349-1354.

Research output: Contribution to journalArticle

Andrade, SE, Davis, R, Cheetham, TC, Cooper, WO, Li, DK, Amini, T, Beaton, SJ, Dublin, S, Hammad, TA, Pawloski, PA, Raebel, MA, Smith, DH, Staffa, JA, Toh, S, Dashevsky, I, Haffenreffer, K, Lane, K, Platt, R & Scott, PE 2012, 'Medication exposure in pregnancy risk evaluation program', Maternal and child health journal, vol. 16, no. 7, pp. 1349-1354. https://doi.org/10.1007/s10995-011-0902-x
Andrade, Susan E. ; Davis, Robert ; Cheetham, T. Craig ; Cooper, William O. ; Li, De Kun ; Amini, Thushi ; Beaton, Sarah J. ; Dublin, Sascha ; Hammad, Tarek A. ; Pawloski, Pamala A. ; Raebel, Marsha A. ; Smith, David H. ; Staffa, Judy A. ; Toh, Sengwee ; Dashevsky, Inna ; Haffenreffer, Katherine ; Lane, Kimberly ; Platt, Richard ; Scott, Pamela E. / Medication exposure in pregnancy risk evaluation program. In: Maternal and child health journal. 2012 ; Vol. 16, No. 7. pp. 1349-1354.
@article{ac759f7815734fdcb66328a60756287c,
title = "Medication exposure in pregnancy risk evaluation program",
abstract = "To describe a program to study medication safety in pregnancy, the Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP). MEPREP is a multisite collaborative research program developed to enable the conduct of studies of medication use and outcomes in pregnancy. Collaborators include the U.S. Food and Drug Administration and researchers at the HMO Research Network, Kaiser Permanente Northern and Southern California, and Vanderbilt University. Datasets have been created at each site linking healthcare data for women delivering an infant between January 1, 2001 and December 31, 2008 and infants born to these women. Standardized data files include maternal and infant characteristics, medication use, and medical care at 11 health plans within 9 states; birth certificate data were obtained from the state departments of public health. MEPREP currently involves more than 20 medication safety researchers and includes data for 1,221,156 children delivered to 933,917 mothers. Current studies include evaluations of the prevalence and patterns of use of specific medications and a validation study of data elements in the administrative and birth certificate data files. MEPREP can support multiple studies by providing information on a large, ethnically and geographically diverse population. This partnership combines clinical and research expertise and data resources to enable the evaluation of outcomes associated with medication use during pregnancy.",
author = "Andrade, {Susan E.} and Robert Davis and Cheetham, {T. Craig} and Cooper, {William O.} and Li, {De Kun} and Thushi Amini and Beaton, {Sarah J.} and Sascha Dublin and Hammad, {Tarek A.} and Pawloski, {Pamala A.} and Raebel, {Marsha A.} and Smith, {David H.} and Staffa, {Judy A.} and Sengwee Toh and Inna Dashevsky and Katherine Haffenreffer and Kimberly Lane and Richard Platt and Scott, {Pamela E.}",
year = "2012",
month = "10",
day = "1",
doi = "10.1007/s10995-011-0902-x",
language = "English (US)",
volume = "16",
pages = "1349--1354",
journal = "Maternal and Child Health Journal",
issn = "1092-7875",
publisher = "Springer GmbH & Co, Auslieferungs-Gesellschaf",
number = "7",

}

TY - JOUR

T1 - Medication exposure in pregnancy risk evaluation program

AU - Andrade, Susan E.

AU - Davis, Robert

AU - Cheetham, T. Craig

AU - Cooper, William O.

AU - Li, De Kun

AU - Amini, Thushi

AU - Beaton, Sarah J.

AU - Dublin, Sascha

AU - Hammad, Tarek A.

AU - Pawloski, Pamala A.

AU - Raebel, Marsha A.

AU - Smith, David H.

AU - Staffa, Judy A.

AU - Toh, Sengwee

AU - Dashevsky, Inna

AU - Haffenreffer, Katherine

AU - Lane, Kimberly

AU - Platt, Richard

AU - Scott, Pamela E.

PY - 2012/10/1

Y1 - 2012/10/1

N2 - To describe a program to study medication safety in pregnancy, the Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP). MEPREP is a multisite collaborative research program developed to enable the conduct of studies of medication use and outcomes in pregnancy. Collaborators include the U.S. Food and Drug Administration and researchers at the HMO Research Network, Kaiser Permanente Northern and Southern California, and Vanderbilt University. Datasets have been created at each site linking healthcare data for women delivering an infant between January 1, 2001 and December 31, 2008 and infants born to these women. Standardized data files include maternal and infant characteristics, medication use, and medical care at 11 health plans within 9 states; birth certificate data were obtained from the state departments of public health. MEPREP currently involves more than 20 medication safety researchers and includes data for 1,221,156 children delivered to 933,917 mothers. Current studies include evaluations of the prevalence and patterns of use of specific medications and a validation study of data elements in the administrative and birth certificate data files. MEPREP can support multiple studies by providing information on a large, ethnically and geographically diverse population. This partnership combines clinical and research expertise and data resources to enable the evaluation of outcomes associated with medication use during pregnancy.

AB - To describe a program to study medication safety in pregnancy, the Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP). MEPREP is a multisite collaborative research program developed to enable the conduct of studies of medication use and outcomes in pregnancy. Collaborators include the U.S. Food and Drug Administration and researchers at the HMO Research Network, Kaiser Permanente Northern and Southern California, and Vanderbilt University. Datasets have been created at each site linking healthcare data for women delivering an infant between January 1, 2001 and December 31, 2008 and infants born to these women. Standardized data files include maternal and infant characteristics, medication use, and medical care at 11 health plans within 9 states; birth certificate data were obtained from the state departments of public health. MEPREP currently involves more than 20 medication safety researchers and includes data for 1,221,156 children delivered to 933,917 mothers. Current studies include evaluations of the prevalence and patterns of use of specific medications and a validation study of data elements in the administrative and birth certificate data files. MEPREP can support multiple studies by providing information on a large, ethnically and geographically diverse population. This partnership combines clinical and research expertise and data resources to enable the evaluation of outcomes associated with medication use during pregnancy.

UR - http://www.scopus.com/inward/record.url?scp=84871676580&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84871676580&partnerID=8YFLogxK

U2 - 10.1007/s10995-011-0902-x

DO - 10.1007/s10995-011-0902-x

M3 - Article

VL - 16

SP - 1349

EP - 1354

JO - Maternal and Child Health Journal

JF - Maternal and Child Health Journal

SN - 1092-7875

IS - 7

ER -