Memphis Girls health Enrichment Multi-site Studies (GEMS). Phase 2

Design and baseline

Robert Klesges, Eva Obarzanek, Lisa M. Klesges, Michelle B. Stockton, Bettina M. Beech, David M. Murray, Jennifer Q. Lanctot, Deborah A. Sherrill-Mittleman

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Obesity prevalence is increasing in the U.S., especially among children and minority populations. This report describes the design and baseline data of the ongoing Girls health Enrichment Multi-site Studies (GEMS) trial (Memphis site), which is testing the efficacy of a 2-year family-based intervention to reduce excessive increase in body mass index (BMI). This randomized, controlled trial conducted at community centers in Memphis, Tennessee requires major measurements at baseline and at 12 and 24 months post-randomization. The participants are healthy African-American girls and one parent/caregiver of each girl. Participating girls are of ages 8-10 years, with BMI ≥ 25th percentile of the CDC 2000 growth charts or with one overweight or obese parent/caregiver (BMI ≥ 25 kg/m2). The active intervention is designed to prevent excessive weight gain by promoting healthy eating habits and increasing physical activity. An alternative intervention (comparison group) promotes general self-esteem and social efficacy. The main outcome measure is the difference between the two treatment groups in the change in BMI at 2 years. Three hundred and three girls have been randomly assigned to receive the test intervention (n = 153) or the alternative intervention (n = 150). The two groups do not differ in baseline characteristics. At the time of enrollment, the mean age was 9 years, the mean BMI was 22 kg/m2 (mean BMI percentile = 77th), and 41% were overweight (BMI ≥ 95th percentile using CDC 2000 growth charts). Participants' intake of fruits and vegetables (1.3 serving/day) and fats (36% kcal), and their participation in moderate-to-vigorous physical activity (20 min/day), did not meet national recommendations. The GEMS obesity prevention intervention targets improved diet and increased physical activity to reduce excessive weight gain in healthy African-American girls of ages 8-10.

Original languageEnglish (US)
Pages (from-to)42-55
Number of pages14
JournalContemporary Clinical Trials
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2008

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Body Mass Index
Health
Growth Charts
Exercise
Centers for Disease Control and Prevention (U.S.)
African Americans
Caregivers
Weight Gain
Obesity
Feeding Behavior
Random Allocation
Self Concept
Vegetables
Fruit
Healthy Volunteers
Randomized Controlled Trials
Fats
Outcome Assessment (Health Care)
Diet
Population

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

Cite this

Klesges, R., Obarzanek, E., Klesges, L. M., Stockton, M. B., Beech, B. M., Murray, D. M., ... Sherrill-Mittleman, D. A. (2008). Memphis Girls health Enrichment Multi-site Studies (GEMS). Phase 2: Design and baseline. Contemporary Clinical Trials, 29(1), 42-55. https://doi.org/10.1016/j.cct.2007.05.001

Memphis Girls health Enrichment Multi-site Studies (GEMS). Phase 2 : Design and baseline. / Klesges, Robert; Obarzanek, Eva; Klesges, Lisa M.; Stockton, Michelle B.; Beech, Bettina M.; Murray, David M.; Lanctot, Jennifer Q.; Sherrill-Mittleman, Deborah A.

In: Contemporary Clinical Trials, Vol. 29, No. 1, 01.01.2008, p. 42-55.

Research output: Contribution to journalArticle

Klesges, R, Obarzanek, E, Klesges, LM, Stockton, MB, Beech, BM, Murray, DM, Lanctot, JQ & Sherrill-Mittleman, DA 2008, 'Memphis Girls health Enrichment Multi-site Studies (GEMS). Phase 2: Design and baseline', Contemporary Clinical Trials, vol. 29, no. 1, pp. 42-55. https://doi.org/10.1016/j.cct.2007.05.001
Klesges R, Obarzanek E, Klesges LM, Stockton MB, Beech BM, Murray DM et al. Memphis Girls health Enrichment Multi-site Studies (GEMS). Phase 2: Design and baseline. Contemporary Clinical Trials. 2008 Jan 1;29(1):42-55. https://doi.org/10.1016/j.cct.2007.05.001
Klesges, Robert ; Obarzanek, Eva ; Klesges, Lisa M. ; Stockton, Michelle B. ; Beech, Bettina M. ; Murray, David M. ; Lanctot, Jennifer Q. ; Sherrill-Mittleman, Deborah A. / Memphis Girls health Enrichment Multi-site Studies (GEMS). Phase 2 : Design and baseline. In: Contemporary Clinical Trials. 2008 ; Vol. 29, No. 1. pp. 42-55.
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