Metastatic VIPoma presenting as an ovarian mass

Jaron Mark, Stephen Bush, Evan Glazer, Jonathan Strosberg, Ozlen Saglam, Sachin M. Apte

Research output: Contribution to journalArticle

Abstract

Introduction Pancreatic VIPomas are exceedingly rare, with an annual incidence of less than 1 per million. Most VIPomas are metastatic at diagnosis, with the liver being the most common site of spread. Presentation of case We describe a highly unusual case of a metastatic pancreatic VIPoma to an ovary in a 54 year-old patient. She was ten years out from her initial diagnosis when routine CT scan showed an enlarging left adnexal mass. After having both ovaries removed laparoscopically the final pathology was consistent with her pancreatic primary. To our knowledge, there has been only one other such case described in the literature. Discussion In this case, pathology revealed metastatic neuroendocrine tumor involving both the left and right ovaries despite only the right ovary apparently enlarging. In our literature search, only two other cases of metastatic PNET to the ovaries have been reported. One case was a glucagonoma and the other a VIPoma. We recommend that clinicians consider referral of patients with metastatic NET and ovarian metastases to gynecologic surgery for consideration of surgical resection. Conclusion In conclusion, this case proves that although uncommon, PNET can show metastases in both ovaries even a decade after initial diagnosis.

Original languageEnglish (US)
Pages (from-to)167-169
Number of pages3
JournalInternational Journal of Surgery Case Reports
Volume17
DOIs
StatePublished - Jan 1 2015

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Vipoma
Ovary
Primitive Neuroectodermal Tumors
Glucagonoma
Pathology
Neoplasm Metastasis
Gynecologic Surgical Procedures
Neuroendocrine Tumors
Referral and Consultation
Liver
Incidence

All Science Journal Classification (ASJC) codes

  • Surgery

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Metastatic VIPoma presenting as an ovarian mass. / Mark, Jaron; Bush, Stephen; Glazer, Evan; Strosberg, Jonathan; Saglam, Ozlen; Apte, Sachin M.

In: International Journal of Surgery Case Reports, Vol. 17, 01.01.2015, p. 167-169.

Research output: Contribution to journalArticle

Mark, Jaron ; Bush, Stephen ; Glazer, Evan ; Strosberg, Jonathan ; Saglam, Ozlen ; Apte, Sachin M. / Metastatic VIPoma presenting as an ovarian mass. In: International Journal of Surgery Case Reports. 2015 ; Vol. 17. pp. 167-169.
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