MiR2GO: Comparative functional analysis for microRNAs

Anindya Bhattacharya, Yan Cui

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Summary: miR2GO is a web-based platform for comparative analyses of human miRNA functions. It includes two programs: miRmut2GO and miRpair2GO. miRmut2GO implements a knowledgebased method to assess the functional effects of genetic and somatic mutations in microRNA seed regions. The functional effects of a mutation are analysed by semantic comparison of enriched gene ontology (GO) annotations of the target gene sets for the wild-type and mutated alleles. miRpair2GO compares the functions of two different miRNAs based on the enriched functional annotations of their target gene sets.

Original languageEnglish (US)
Pages (from-to)2403-2405
Number of pages3
JournalBioinformatics
Volume31
Issue number14
DOIs
StatePublished - Jan 1 2015

Fingerprint

Functional analysis
MicroRNA
Functional Analysis
MicroRNAs
Comparative Analysis
Genes
Annotation
Mutation
Gene
Molecular Sequence Annotation
Gene Ontology
Target
Knowledge-based
Semantics
Web-based
Ontology
Seed
Seeds
Alleles

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

Cite this

MiR2GO : Comparative functional analysis for microRNAs. / Bhattacharya, Anindya; Cui, Yan.

In: Bioinformatics, Vol. 31, No. 14, 01.01.2015, p. 2403-2405.

Research output: Contribution to journalArticle

Bhattacharya, Anindya ; Cui, Yan. / MiR2GO : Comparative functional analysis for microRNAs. In: Bioinformatics. 2015 ; Vol. 31, No. 14. pp. 2403-2405.
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