Multi-area integrated E/MEG and fMRI modeling

Abbas Babajani-Feremi, Susan Bowyer, John Moran, Kost Elisevich, Kenneth Podell, Hamid Soltanian-Zadeh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Functional magnetic resonance imaging (fMRI) has complementary spatiotemporal resolution compared to Electroencephalography (EEG) as well as Magnetoencephalography (MEG). Thus, their integrated analysis should improve the overall resolution. To integrate analysis of E/MEG and fMRI, we extend our previously proposed integrated E/MEG and fMRI neural mass model to a multi-area model by defining two types of connections: the Short-Range Connections (SRCs) between minicolumns within the areas and Long-Range Connections (LRCs) between inter-areas minicolumns. The nonlinear input/output relationship in the proposed model is derived from the state space representation of the multi-area model. The E/MEG signals are originated from the overall synaptic activities of the pyramidal cells of all minicolumns and can be calculated using the lead field matrix (i.e., forward electromagnetic model). The fMRI signal is extracted from the proposed integrated model by calculating the overall neural activities in the areas and using it as the input of the extended balloon model (EBM). Using the simulation results, the capabilities of the proposed model to generate E/MEG and fMRI signals is shown. In addition, changes in the dynamics of the model to variations of its parameters were evaluated and lead us to the appropriate ranges for the parameters. In conclusion, this work proposes an effective method to integrate E/MEG and fMRI for the more effective use of these techniques in functional neuroimaging.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2009
Subtitle of host publicationBiomedical Applications in Molecular, Structural, and Functional Imaging
Volume7262
DOIs
StatePublished - Jun 22 2009
Externally publishedYes
EventMedical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging - Lake Buena Vista, FL, United States
Duration: Feb 8 2009Feb 10 2009

Other

OtherMedical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging
CountryUnited States
CityLake Buena Vista, FL
Period2/8/092/10/09

Fingerprint

Magnetoencephalography
magnetic resonance
Magnetic Resonance Imaging
Functional Neuroimaging
Pyramidal Cells
Electromagnetic Phenomena
Functional neuroimaging
Electroencephalography
electroencephalography
Balloons
balloons
Lead
Cells
electromagnetism

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Babajani-Feremi, A., Bowyer, S., Moran, J., Elisevich, K., Podell, K., & Soltanian-Zadeh, H. (2009). Multi-area integrated E/MEG and fMRI modeling. In Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging (Vol. 7262). [72621V] https://doi.org/10.1117/12.813801

Multi-area integrated E/MEG and fMRI modeling. / Babajani-Feremi, Abbas; Bowyer, Susan; Moran, John; Elisevich, Kost; Podell, Kenneth; Soltanian-Zadeh, Hamid.

Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 7262 2009. 72621V.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Babajani-Feremi, A, Bowyer, S, Moran, J, Elisevich, K, Podell, K & Soltanian-Zadeh, H 2009, Multi-area integrated E/MEG and fMRI modeling. in Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging. vol. 7262, 72621V, Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging, Lake Buena Vista, FL, United States, 2/8/09. https://doi.org/10.1117/12.813801
Babajani-Feremi A, Bowyer S, Moran J, Elisevich K, Podell K, Soltanian-Zadeh H. Multi-area integrated E/MEG and fMRI modeling. In Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 7262. 2009. 72621V https://doi.org/10.1117/12.813801
Babajani-Feremi, Abbas ; Bowyer, Susan ; Moran, John ; Elisevich, Kost ; Podell, Kenneth ; Soltanian-Zadeh, Hamid. / Multi-area integrated E/MEG and fMRI modeling. Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 7262 2009.
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