Multicenter in vitro comparison of piperacillin and nine other antibacterials against 1,629 clinical isolates

R. N. Greenberg, D. B. Bowne, Michael Gelfand, S. S. Sathe

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The antibacterial spectrum of activity of piperacillin was compared with that of other antibiotics against isolates of Escherichia coli, Enterobacter cloacae, Haemophilus influenzae, Klebsiella pneumoniae, Pseudomonas aeruginosa, Pseudomonas cepacia, Pseudomonas maltophilia, Serratia marcescens, Enterococcus sp, Bacteroides fragilis, Bacteroides bivius, and Clostridium difficile, obtained from laboratories at hospitals in St. Louis, in Memphis, and in Newark, New Jersey. Of the 1,629 isolates tested, 91% were susceptible to piperacillin, 90% to mezlocillin, 87% to ticarcillin/clavulanate and imipenem, 83% to ceftazidime, 81% to cefoperazone, 80% to ciprofloxacin, 77% to ceftriaxone, 71% to aztreonam, and 51% to cefoxitin.

Original languageEnglish (US)
Pages (from-to)61-70
Number of pages10
JournalClinical Therapeutics
Volume12
Issue number1
StatePublished - Mar 23 1990
Externally publishedYes

Fingerprint

Piperacillin
Mezlocillin
Stenotrophomonas maltophilia
Ticarcillin
Burkholderia cepacia
Aztreonam
Cefoperazone
Enterobacter cloacae
Cefoxitin
Bacteroides fragilis
Hospital Laboratories
Clavulanic Acid
Serratia marcescens
Bacteroides
Ceftazidime
Clostridium difficile
Ceftriaxone
Imipenem
Enterococcus
Haemophilus influenzae

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)

Cite this

Multicenter in vitro comparison of piperacillin and nine other antibacterials against 1,629 clinical isolates. / Greenberg, R. N.; Bowne, D. B.; Gelfand, Michael; Sathe, S. S.

In: Clinical Therapeutics, Vol. 12, No. 1, 23.03.1990, p. 61-70.

Research output: Contribution to journalArticle

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