Multimodality functional imaging evaluation in a patient with Rasmussen's encephalitis

Hideaki Ishibashi, Panagiotis G. Simos, James Wheless, James E. Baumgartner, Howard L. Kim, Robert N. Davis, Wenbo Zhang, Andrew Papanicolaou

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Rasmussen's encephalitis (RE) is a cryptogenic progressive inflammatory disorder of the brain that causes severe neurological problems, including intractable focal epilepsy. In select patients, aggressive treatment using cerebral hemispherectomy may ameliorate the devastating cognitive decline that accompanies this disease, even if the epileptic focus appears broadly distributed. We present a case of histopathologically-confirmed RE evaluated using a multimodal process that explored the physical and functional aspects of the associated epilepsy. This process included magnetic resonance imaging, single photo emission computed tomography, electroencephalography, and magnetoencephalography (MEG). The findings indicate that functional brain imaging data may greatly assist the surgical treatment decision-making process in RE, especially when structural imaging fails to reveal definitive localizing information. In addition, MEG may provide insights about the cortical reorganization of somatosensory cortex following hemispherectomy.

Original languageEnglish (US)
Pages (from-to)239-244
Number of pages6
JournalBrain and Development
Volume24
Issue number4
DOIs
StatePublished - Jun 4 2002

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Encephalitis
Hemispherectomy
Magnetoencephalography
Emission-Computed Tomography
Physical Phenomena
Functional Neuroimaging
Somatosensory Cortex
Partial Epilepsy
Brain Diseases
Electroencephalography
Epilepsy
Decision Making
Magnetic Resonance Imaging
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology

Cite this

Ishibashi, H., Simos, P. G., Wheless, J., Baumgartner, J. E., Kim, H. L., Davis, R. N., ... Papanicolaou, A. (2002). Multimodality functional imaging evaluation in a patient with Rasmussen's encephalitis. Brain and Development, 24(4), 239-244. https://doi.org/10.1016/S0387-7604(02)00036-0

Multimodality functional imaging evaluation in a patient with Rasmussen's encephalitis. / Ishibashi, Hideaki; Simos, Panagiotis G.; Wheless, James; Baumgartner, James E.; Kim, Howard L.; Davis, Robert N.; Zhang, Wenbo; Papanicolaou, Andrew.

In: Brain and Development, Vol. 24, No. 4, 04.06.2002, p. 239-244.

Research output: Contribution to journalArticle

Ishibashi, H, Simos, PG, Wheless, J, Baumgartner, JE, Kim, HL, Davis, RN, Zhang, W & Papanicolaou, A 2002, 'Multimodality functional imaging evaluation in a patient with Rasmussen's encephalitis', Brain and Development, vol. 24, no. 4, pp. 239-244. https://doi.org/10.1016/S0387-7604(02)00036-0
Ishibashi, Hideaki ; Simos, Panagiotis G. ; Wheless, James ; Baumgartner, James E. ; Kim, Howard L. ; Davis, Robert N. ; Zhang, Wenbo ; Papanicolaou, Andrew. / Multimodality functional imaging evaluation in a patient with Rasmussen's encephalitis. In: Brain and Development. 2002 ; Vol. 24, No. 4. pp. 239-244.
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