Multiple endocrine neoplasia type 2 syndrome presenting with bowel obstruction caused by intestinal neuroma

Case report

Maitreyi Prabhu, Rami Khouzam, Jonathan Insel

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We present the case of a 23-year-old male with a history since early childhood of lip and tongue mucosal neuromas. At the age of 19, he was diagnosed with both medullary thyroid carcinoma and pheochromocytoma within 1 year. These findings, with his marfanoid habitus, led to the diagnosis of multiple endocrine neoplasia ype 2 (MEN 2B) syndrome. This was confirmed by a positive RET proto-oncogene. On this admission, he presented with an intestinal obstruction. Abdominal exploration revealed an obstructing tumor mass requiring colectomy, which proved by biopsy to be an intestinal neuroma. This report presents a unique case of a colonic mucosal neuroma causing obstruction in MEN 2B syndrome after the diagnosis of medullary thyroid carcinoma.

Original languageEnglish (US)
Pages (from-to)1130-1132
Number of pages3
JournalSouthern Medical Journal
Volume97
Issue number11
DOIs
StatePublished - Nov 1 2004
Externally publishedYes

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Multiple Endocrine Neoplasia Type 2a
Multiple Endocrine Neoplasia
Neuroma
Intestinal Obstruction
Multiple Endocrine Neoplasia Type 2b
Proto-Oncogenes
Colectomy
Pheochromocytoma
Lip
Tongue
History
Biopsy
Neoplasms
Medullary Thyroid cancer

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Multiple endocrine neoplasia type 2 syndrome presenting with bowel obstruction caused by intestinal neuroma : Case report. / Prabhu, Maitreyi; Khouzam, Rami; Insel, Jonathan.

In: Southern Medical Journal, Vol. 97, No. 11, 01.11.2004, p. 1130-1132.

Research output: Contribution to journalArticle

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