Myxoid liposarcoma

A case report of a sentinel metastasis to the parotid gland with molecular confirmation

Laura Been, Adriana Olar, Martin P. Powers, Dolores López-Terrada, Rodolfo Laucirica

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Myxoid liposarcoma is a subtype of liposarcoma with a predilection for the deep soft tissues of the extremities that accounts approximately for 10% of all adult soft tissue sarcomas. We report a case of a metastatic myxoid liposarcoma to the parotid gland, with fine-needle aspiration cytology correlation and molecular characterization. The lesion was diagnosed in a 53-year-old Hispanic male who presented with a left posterior thigh mass. A core needle biopsy established the diagnosis of myxoid liposarcoma. The patient underwent limb-sparing, wide local excision of the malignancy and later presented with an initial metastatic lesion to the parotid gland. The diagnosis of metastatic myxoid liposarcoma was rendered by fine-needle aspiration cytology with cell block preparation, and molecular confirmation. Although myxoid/round cell liposarcomas are classically described as having minimal pleomorphism on cytologic material, we encountered significant pleomorphism in our case. Therefore, a diagnosis of myxoid/round cell liposarcoma should still be a diagnostic consideration even if markedly pleomorphic cells are seen in fine-needle aspiration biopsies. Diagn. Cytopathol.

Original languageEnglish (US)
Pages (from-to)780-783
Number of pages4
JournalDiagnostic Cytopathology
Volume39
Issue number10
DOIs
StatePublished - Oct 1 2011
Externally publishedYes

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Myxoid Liposarcoma
Parotid Gland
Liposarcoma
Fine Needle Biopsy
Neoplasm Metastasis
Cell Biology
Extremities
Large-Core Needle Biopsy
Thigh
Hispanic Americans
Sarcoma
cyhalothrin
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

Cite this

Myxoid liposarcoma : A case report of a sentinel metastasis to the parotid gland with molecular confirmation. / Been, Laura; Olar, Adriana; Powers, Martin P.; López-Terrada, Dolores; Laucirica, Rodolfo.

In: Diagnostic Cytopathology, Vol. 39, No. 10, 01.10.2011, p. 780-783.

Research output: Contribution to journalArticle

Been, Laura ; Olar, Adriana ; Powers, Martin P. ; López-Terrada, Dolores ; Laucirica, Rodolfo. / Myxoid liposarcoma : A case report of a sentinel metastasis to the parotid gland with molecular confirmation. In: Diagnostic Cytopathology. 2011 ; Vol. 39, No. 10. pp. 780-783.
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