Near infrared spectroscopy (NIRS) distinguishes seizure types

D. K. Sokol, O. N. Markand, E. C. Daly, T. G. Luerssen, Marc Malkoff

Research output: Contribution to journalArticle

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Abstract

Near infrared spectroscopy (NIRS) is a noninvasive method for bedside measurement of cerebral oxygenation (SaO2). The purpose of this study was to establish differences in SaO2 for complex partial seizures (CPS) and rapidly secondarily generalized CPS (RCPS). We studied eight adults with medically refractory epilepsy undergoing evaluation for temporal lobectomy. We continually measured cerebral SaO2 via a Somanetic Invos 3100a cerebral oximeter, pre-ictal (5 minutes), ictal, immediate (30 seconds) post-ictal, and late post-ictal (5 minutes after ictus). Seventeen seizures (12 CPS, four RCPS and one subclinical) were recorded in eight patients. The percentage change in cerebral SaO2 from pre-ictal to ictal periods was derived. Cerebral SaO2 increased (percentage change, mean: 16.6, SD: 13.9) for CPS and decreased (percentage change, mean: 51.1, SD: 18.1) for RCPS. No change in cerebral oximetry was recorded for the subclinical seizure. Post-ictal (immediate and late) increase in cerebral SaO2 was seen for 11 of the 17 seizures (nine CPS and two RCPS). Peripheral SaO2 rose greater than 93% for all CPS and the subclinical seizure, but decreased between 78 and 84% during RCPS. These results suggest NIRS distinguishes cerebral SaO2 patterns between CPS and RCPS. The decrease in peripheral SaO2, however, may account for the decrease in cerebral SaO2 seen in generalized seizures. (C) 2000 BEA Trading Ltd.

Original languageEnglish (US)
Pages (from-to)323-327
Number of pages5
JournalSeizure
Volume9
Issue number5
DOIs
StatePublished - Jan 1 2000

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Near-Infrared Spectroscopy
Seizures
Stroke
Partial Epilepsy
Oximetry
Epilepsy

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Sokol, D. K., Markand, O. N., Daly, E. C., Luerssen, T. G., & Malkoff, M. (2000). Near infrared spectroscopy (NIRS) distinguishes seizure types. Seizure, 9(5), 323-327. https://doi.org/10.1053/seiz.2000.0406

Near infrared spectroscopy (NIRS) distinguishes seizure types. / Sokol, D. K.; Markand, O. N.; Daly, E. C.; Luerssen, T. G.; Malkoff, Marc.

In: Seizure, Vol. 9, No. 5, 01.01.2000, p. 323-327.

Research output: Contribution to journalArticle

Sokol, DK, Markand, ON, Daly, EC, Luerssen, TG & Malkoff, M 2000, 'Near infrared spectroscopy (NIRS) distinguishes seizure types', Seizure, vol. 9, no. 5, pp. 323-327. https://doi.org/10.1053/seiz.2000.0406
Sokol, D. K. ; Markand, O. N. ; Daly, E. C. ; Luerssen, T. G. ; Malkoff, Marc. / Near infrared spectroscopy (NIRS) distinguishes seizure types. In: Seizure. 2000 ; Vol. 9, No. 5. pp. 323-327.
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