Neonatal Enterovirus Myocarditis With Severe Dystrophic Calcification: Novel Treatment With Pocapavir

Samuel G. Wittekind, Catherine C. Allen, John Jefferies, Mantosh S. Rattan, Peace C. Madueme, Bre Ann N. Taylor, Ryan A. Moore

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Dystrophic myocardial calcification occurs in the setting of myocardial injury and normal serum calcium. We present a case of a neonate with prominent dystrophic calcification and severe left ventricular systolic dysfunction in the setting of enterovirus myocarditis. These findings are superbly illustrated by multiple imaging modalities. The patient was treated with the novel antiviral, pocapavir, in addition to a standard heart failure regimen. The dystrophic calcification persisted but the left ventricle remodeled significantly. To our knowledge, this is the first reported use of pocapavir for this indication. The literature regarding enterovirus myocarditis and pocapavir is briefly reviewed.

Original languageEnglish (US)
JournalJournal of Investigative Medicine High Impact Case Reports
Volume5
Issue number3
DOIs
StatePublished - Sep 1 2017

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Enterovirus
Myocarditis
indication
Calcium
Imaging techniques
Left Ventricular Dysfunction
Heart Ventricles
Antiviral Agents
Heart Failure
Newborn Infant
Wounds and Injuries
Therapeutics
Serum
literature

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Safety, Risk, Reliability and Quality
  • Safety Research

Cite this

Neonatal Enterovirus Myocarditis With Severe Dystrophic Calcification : Novel Treatment With Pocapavir. / Wittekind, Samuel G.; Allen, Catherine C.; Jefferies, John; Rattan, Mantosh S.; Madueme, Peace C.; Taylor, Bre Ann N.; Moore, Ryan A.

In: Journal of Investigative Medicine High Impact Case Reports, Vol. 5, No. 3, 01.09.2017.

Research output: Contribution to journalArticle

Wittekind, Samuel G. ; Allen, Catherine C. ; Jefferies, John ; Rattan, Mantosh S. ; Madueme, Peace C. ; Taylor, Bre Ann N. ; Moore, Ryan A. / Neonatal Enterovirus Myocarditis With Severe Dystrophic Calcification : Novel Treatment With Pocapavir. In: Journal of Investigative Medicine High Impact Case Reports. 2017 ; Vol. 5, No. 3.
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