Nerve repair by means of tubulization

Past, present, future

Petros Konofaos, J. P. Ver Halen

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

Peripheral nerve injury may result in injury without gaps or injury with gaps between nerve stumps. In the presence of a nerve defect, the placement of an autologous nerve graft is the current gold standard for nerve restoration. The clinical employment of tubes as an alternative to autogenous nerve grafts is mainly justified by the limited availability of donor tissue for nerve autografts and their related morbidity. The purpose of this review is to present an overview of the literature on the applications of nerve conduits in peripheral nerve repair. Moreover, the different steps that are involved in the design of an ideal nerve conduit for peripheral nerve repair, including the choice of biomaterial, fabrication technique, and the various potential modifications to the common hollow nerve tube, are also discussed.

Original languageEnglish (US)
Pages (from-to)149-163
Number of pages15
JournalJournal of Reconstructive Microsurgery
Volume29
Issue number3
DOIs
StatePublished - 2013
Externally publishedYes

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Peripheral Nerves
Transplants
Nerve Tissue
Peripheral Nerve Injuries
Autografts
Wounds and Injuries
Biocompatible Materials
Tissue Donors
Morbidity

All Science Journal Classification (ASJC) codes

  • Surgery
  • Medicine(all)

Cite this

Nerve repair by means of tubulization : Past, present, future. / Konofaos, Petros; Ver Halen, J. P.

In: Journal of Reconstructive Microsurgery, Vol. 29, No. 3, 2013, p. 149-163.

Research output: Contribution to journalArticle

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