Neural mechanisms underlying auditory feedback control of speech

Jason A. Tourville, Kevin Reilly, Frank H. Guenther

Research output: Contribution to journalArticle

289 Citations (Scopus)

Abstract

The neural substrates underlying auditory feedback control of speech were investigated using a combination of functional magnetic resonance imaging (fMRI) and computational modeling. Neural responses were measured while subjects spoke monosyllabic words under two conditions: (i) normal auditory feedback of their speech and (ii) auditory feedback in which the first formant frequency of their speech was unexpectedly shifted in real time. Acoustic measurements showed compensation to the shift within approximately 136 ms of onset. Neuroimaging revealed increased activity in bilateral superior temporal cortex during shifted feedback, indicative of neurons coding mismatches between expected and actual auditory signals, as well as right prefrontal and Rolandic cortical activity. Structural equation modeling revealed increased influence of bilateral auditory cortical areas on right frontal areas during shifted speech, indicating that projections from auditory error cells in posterior superior temporal cortex to motor correction cells in right frontal cortex mediate auditory feedback control of speech.

Original languageEnglish (US)
Pages (from-to)1429-1443
Number of pages15
JournalNeuroImage
Volume39
Issue number3
DOIs
StatePublished - Feb 1 2008

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Temporal Lobe
Auditory Cortex
Frontal Lobe
Acoustics
Neuroimaging
Magnetic Resonance Imaging
Neurons

All Science Journal Classification (ASJC) codes

  • Neurology
  • Cognitive Neuroscience

Cite this

Neural mechanisms underlying auditory feedback control of speech. / Tourville, Jason A.; Reilly, Kevin; Guenther, Frank H.

In: NeuroImage, Vol. 39, No. 3, 01.02.2008, p. 1429-1443.

Research output: Contribution to journalArticle

Tourville, Jason A. ; Reilly, Kevin ; Guenther, Frank H. / Neural mechanisms underlying auditory feedback control of speech. In: NeuroImage. 2008 ; Vol. 39, No. 3. pp. 1429-1443.
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