Neurodegenerative disorders

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder clinically characterized by the presence of choreiform movements, psychiatric sequelae, and dementia. While the majority (>90%) of HD patients become clinically symptomatic in adulthood, 5% to 10% of patients present with the juvenile-onset form of the disease, which is almost invariably associated with inheritance of the mutant allele from a symptomatic father. Unlike the adult-onset form of the disease, juvenile HD is generally characterized by the presence of progressive rigidity, seizures, ataxia, and dystonia.

Original languageEnglish (US)
Title of host publicationMolecular Pathology in Clinical Practice
PublisherSpringer New York
Pages179-189
Number of pages11
ISBN (Print)038733226X, 9780387332260
DOIs
StatePublished - Dec 1 2007
Externally publishedYes

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Huntington Disease
Neurodegenerative Diseases
Chorea
Dystonia
Ataxia
Fathers
Psychiatry
Dementia
Seizures
Alleles

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Potter, N. (2007). Neurodegenerative disorders. In Molecular Pathology in Clinical Practice (pp. 179-189). Springer New York. https://doi.org/10.1007/978-0-387-33227-7_15

Neurodegenerative disorders. / Potter, Nicholas.

Molecular Pathology in Clinical Practice. Springer New York, 2007. p. 179-189.

Research output: Chapter in Book/Report/Conference proceedingChapter

Potter, N 2007, Neurodegenerative disorders. in Molecular Pathology in Clinical Practice. Springer New York, pp. 179-189. https://doi.org/10.1007/978-0-387-33227-7_15
Potter N. Neurodegenerative disorders. In Molecular Pathology in Clinical Practice. Springer New York. 2007. p. 179-189 https://doi.org/10.1007/978-0-387-33227-7_15
Potter, Nicholas. / Neurodegenerative disorders. Molecular Pathology in Clinical Practice. Springer New York, 2007. pp. 179-189
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