Neurologic complications of disorders of the adrenal glands

Tulio Bertorini, Angel Perez

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Citations (Scopus)

Abstract

Disorders of the adrenal glands frequently have secondary neurological manifestations, while some diseases that involve the central nervous system are accompanied by adrenal gland dysfunction. Excessive corticosteroid secretions in primary or secondary Cushing's syndrome causes muscle weakness and behavioral disturbances, such as emotional lability and sometimes depression, while adrenal insufficiency may cause fatigue, weakness, and depression. Adrenoleukodystrophy and adrenoneuromyelopathy are X-linked recessive disorders of the metabolism of very long chain fatty acids that manifest with white matter abnormalities of the brain, myelopathy and/or neuropathy, as well as adrenal insufficiency. Other disorders of the adrenal glands include hyperaldosteroidism, which may cause weakness from hypokalemia. Dysfunction of the adrenal medulla causes excessive or deficient secretion of catecholamines, primarily causing cardiovascular symptoms.This chapter reviews the clinical manifestations and diagnostic aspects and treatment of the various disorders of the adrenal glands. Some of the congenital adrenal diseases are also discussed.

Original languageEnglish (US)
Title of host publicationHandbook of Clinical Neurology
PublisherElsevier B.V.
Pages749-771
Number of pages23
DOIs
StatePublished - Jan 1 2014

Publication series

NameHandbook of Clinical Neurology
Volume120
ISSN (Print)0072-9752

Fingerprint

Adrenal Glands
Nervous System Diseases
Adrenal Insufficiency
Adrenoleukodystrophy
Adrenal Medulla
Hypokalemia
Cushing Syndrome
Spinal Cord Diseases
Central Nervous System Diseases
Muscle Weakness
Neurologic Manifestations
Catecholamines
Fatigue
Adrenal Cortex Hormones
Fatty Acids
Brain

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Bertorini, T., & Perez, A. (2014). Neurologic complications of disorders of the adrenal glands. In Handbook of Clinical Neurology (pp. 749-771). (Handbook of Clinical Neurology; Vol. 120). Elsevier B.V.. https://doi.org/10.1016/B978-0-7020-4087-0.00050-4

Neurologic complications of disorders of the adrenal glands. / Bertorini, Tulio; Perez, Angel.

Handbook of Clinical Neurology. Elsevier B.V., 2014. p. 749-771 (Handbook of Clinical Neurology; Vol. 120).

Research output: Chapter in Book/Report/Conference proceedingChapter

Bertorini, T & Perez, A 2014, Neurologic complications of disorders of the adrenal glands. in Handbook of Clinical Neurology. Handbook of Clinical Neurology, vol. 120, Elsevier B.V., pp. 749-771. https://doi.org/10.1016/B978-0-7020-4087-0.00050-4
Bertorini T, Perez A. Neurologic complications of disorders of the adrenal glands. In Handbook of Clinical Neurology. Elsevier B.V. 2014. p. 749-771. (Handbook of Clinical Neurology). https://doi.org/10.1016/B978-0-7020-4087-0.00050-4
Bertorini, Tulio ; Perez, Angel. / Neurologic complications of disorders of the adrenal glands. Handbook of Clinical Neurology. Elsevier B.V., 2014. pp. 749-771 (Handbook of Clinical Neurology).
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