Neurologic complications of pancreas and small bowel transplantation

Michael Jacewicz, Christopher R. Marino

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

In the past decade, substantial improvements in patient and graft survival for pancreas and small bowel transplants have been achieved. Despite this progress, many patients still develop neurologic complications in the course of their illness. Small bowel transplants produce more neurologic complications because of the complex metabolic environment in which the procedure is performed and because of the intense immune suppression necessitated by the greater immunogenicity of the intestinal mucosa. Pancreas transplants stabilize and/or improve the signs and symptoms of diabetic neuropathy over time. Because transplantation of the pancreas is often coupled with a kidney transplant and small intestine with liver, neurologic complications in these patients sometimes reflect problems involving the organ partner or both organs. The spectrum of neurologic complications for pancreas and small bowel transplant recipients is similar to other organ transplants but their frequency varies depending on the type of transplant performed.

Original languageEnglish (US)
Title of host publicationHandbook of Clinical Neurology
PublisherElsevier B.V.
Pages1277-1293
Number of pages17
DOIs
StatePublished - Jan 1 2014

Publication series

NameHandbook of Clinical Neurology
Volume121
ISSN (Print)0072-9752

Fingerprint

Nervous System
Pancreas
Transplantation
Transplants
Pancreas Transplantation
Diabetic Neuropathies
Graft Survival
Intestinal Mucosa
Signs and Symptoms
Small Intestine
Kidney
Liver

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Jacewicz, M., & Marino, C. R. (2014). Neurologic complications of pancreas and small bowel transplantation. In Handbook of Clinical Neurology (pp. 1277-1293). (Handbook of Clinical Neurology; Vol. 121). Elsevier B.V.. https://doi.org/10.1016/B978-0-7020-4088-7.00087-0

Neurologic complications of pancreas and small bowel transplantation. / Jacewicz, Michael; Marino, Christopher R.

Handbook of Clinical Neurology. Elsevier B.V., 2014. p. 1277-1293 (Handbook of Clinical Neurology; Vol. 121).

Research output: Chapter in Book/Report/Conference proceedingChapter

Jacewicz, M & Marino, CR 2014, Neurologic complications of pancreas and small bowel transplantation. in Handbook of Clinical Neurology. Handbook of Clinical Neurology, vol. 121, Elsevier B.V., pp. 1277-1293. https://doi.org/10.1016/B978-0-7020-4088-7.00087-0
Jacewicz M, Marino CR. Neurologic complications of pancreas and small bowel transplantation. In Handbook of Clinical Neurology. Elsevier B.V. 2014. p. 1277-1293. (Handbook of Clinical Neurology). https://doi.org/10.1016/B978-0-7020-4088-7.00087-0
Jacewicz, Michael ; Marino, Christopher R. / Neurologic complications of pancreas and small bowel transplantation. Handbook of Clinical Neurology. Elsevier B.V., 2014. pp. 1277-1293 (Handbook of Clinical Neurology).
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